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Found 64,772 clinical trials

The Solaris DE Endoprosthesis for the Treatment of AV Access Stenosis or Occlusion

The goal of this clinical trial is to demonstrate the safety and efficacy of Solaris DE Endoprosthesis in the treatment of stenosis or occlusion within the outflow circuit of the dialysis access including arteriovenous (AV) fistula and synthetic AV graft. Participants will be treated with Solaris DE Endoprosthesis. Researchers will …

18 years of age All Phase N/A

577-nm Diode Laser in the Treatment of Non -Inflammatory Acne

The aim of this study is to evaluate the clinical efficacy and safety of the 577 nm diode laser in the treatment of non -inflammatory acne.

18 - 40 years of age All Phase N/A

Black Resilient Caregivers

To determine the feasibility of an intervention to promote the physical and socioemotional health of African American (AA) families.

18 years of age All Phase N/A
R Ramon Barajas

Evaluation of the Change in PSMA Expression in Prostate Cancer in Response to Hormonal Therapy

This clinical trial investigates the change in prostate-specific membrane antigen (PSMA) expression in response to hormonal therapy in both, Castration Sensitive Prostate Cancer (CSPC) and Castration Resistant Prostate Cancer (CRPC), and whether this change in PSMA expression changes tumor staging after therapy initiation. Understanding these effects can help define the …

18 years of age Male Phase 4
J Julie Burns

A Study of ADRX-0405 in Subjects With Select Advanced Solid Tumors

The primary purpose of this study is to assess the safety, tolerability, and pharmacokinetics, and to identify the optimal dose of ADRX-0405 in patients with select advanced solid tumors.

18 years of age All Phase 1

Efficacy and Safety Study of Halneuron in the Treatment of Chemotherapy-Induced Neuropathic Pain

A randomized study to determine safety and efficacy of single subcutaneous (SC) administration of HAL treatment in patients with CINP.

18 years of age All Phase 2
D Dr Girish Kumar Parida, MD

PET/CT GUIDED BIOPSY VERSUS CT GUIDED BIOPSY IN EVALUATION OF SUSPECTED LUNG NEOPLASMS

Percutaneous CT guided biopsy is a well-established, standard sampling technique for suspected neoplastic lesions located in peripheral region in lung parenchyma. Inconclusive results on CT guided biopsy is substantially higher in large lung lesions which are prone to cause peripheral pneumonia, atelectasis and even regional necrosis, which are hard to …

18 years of age All Phase N/A

The Effect Of Technology Addiction Prevention Program On University Students At Risk For Technology Addiction

Due to the increasing use of technological devices among adolescents, technology addiction is a serious public health problem that requires intervention. In order to cope with this problem, it is necessary to develop programs that have proven effects and are suitable for our culture and the psychosocial development of the …

17 - 24 years of age All Phase N/A
J Jamie Armstrong, MSc

ID93/GLA-SE Vaccination + BCG Challenge

The purpose of this study is to: Demonstrate the safety of a novel TB vaccine (ID93/GLA-SE) when given to both BCG-vaccinated and BCG-naïve volunteers. Provide preliminary immunogenicity data of this novel TB vaccine (ID93/GLA-SE). This clinical trial will apply an aerosol BCG challenge model involving 48 participants - 24 historically …

18 - 55 years of age All Phase N/A

Study Evaluating Dosimetry, Randomized Dose Optimization, Dose Escalation and Efficacy of Ac-225 Rosopatamab Tetraxetan in Participants With PSMA PET-Positive Castration-Resistant Prostate Cancer (CRPC)

This is a three-part study evaluating the safety and efficacy of a PSMA-directed radioantibody (rosopatamab tetraxetan, conjugated to either In-111 or Ac-225). Part 1 will consist of one administration of In-111-rosopatamab tetraxetan to characterize the biodistribution of the radioantibody to target organs and prostate cancer lesions. Participants then will be …

18 years of age Male Phase 2

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