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Found 65,447 clinical trials
D Dina M Fakhry, MD

Predicting Ultrasound-Guided Thoracic PVB Success in Herpetic Neuralgia

This study aims to fill the knowledge gap by investigating the predictors of success for TPVB in patients with herpetic neuralgia. By identifying demographic, clinical, previous medications and procedural factors associated with positive outcomes, this research seeks to enhance the efficacy of TPVB and improve pain management strategies for patients …

18 - 70 years of age All Phase N/A

Probiotics Combined with Enteral Nutrition Reduces Postoperative Infectious Complications in PD

Probiotics combined with enteral nutrition reduces postoperative infectious complications in PD

18 years of age All Phase 1/2
D Denzel LQ Drop, MD

ICU-VR Prior to ICU Admission

Rationale: A substantial proportion of the Intensive Care Unit (ICU) survivors develop psychological impairments due to their ICU admission. Several interventions to mitigate these impairments have been explored but lack a proper effect. Intensive Care Unit-specific Virtual Reality has proven to be potentially effective in treating PTSD and depression-related sequelae …

18 - 71 years of age All Phase N/A
C Coral Omene, MD,PhD

Tirzepatide for Weight Loss Intervention in Early-Stage Hormone Receptor Positive/HER2 Negative Breast Cancer

This clinical trial aims to evaluate the effectiveness of tirzepatide in achieving a 5% or more body weight reduction in patients undergoing adjuvant treatment for hormone receptor-positive, HER2-negative (HR+/Her2-) breast cancer. The study will also assess the safety and tolerability of tirzepatide, its feasibility based on discontinuation rates, and completion …

18 years of age All Phase 2
A Anna W Stenbro, Master's degree in Psychology,

Internet-based Versus Synchronous Cognitive Behavioural Therapy for Patients With Gambling Disorder

The aim of this two-armed, randomized controlled trial is to determine if internet-based cognitive behavioural therapy (CBT) is as effective as synchronous CBT (sCBT) for treating Gambling Disorder (GD) in adults. The main question it aims to answer is: Is the effect of the internet-based CBT ("SpilleFri") non-inferior to that …

18 years of age All Phase N/A
Y Yunfeng Xia, Dr.

The Effect of Active Exercise on Maintenance Haemodialysis Patients

The goal of this clinical trial is to discuss the effects of physical activity on nutrition, inflammation, muscle metabolism, and the occurrence of cardiovascular and cerebrovascular events in patients with maintenance haemodialysis. The main question it aims to answer is: can exercise improve nutritional and inflammatory status, enhance muscle strength, …

18 - 75 years of age All Phase N/A
N Nicole Stevens, PhD

Natural Product System and Lifestyle Modification

The goal of this clinical trial is to learn whether four dietary supplements and lifestyle changes can affect gene expression and blood markers in healthy volunteers. The main questions it aims to answer are: How does daily ingestion of dietary supplements affect gene expression and hsCRP and vitamin D levels …

30 - 55 years of age All Phase N/A
F Freyja A.D Haigh, PhD

The Effect of Ingesting a Novel Algae Protein Source on Rested and Exercised Muscle Protein Synthesis Rates in Older Adults.

To assess the rested and postexercise muscle protein synthetic response following the ingestion of a flavourless algae protein source compared with whey protein in older adults.

65 - 80 years of age All Phase N/A
G Georgia Tsaousi, Professor

Effect of Volatile- Based Versus Total Intravenous Anesthesia on Brain Homeostasis and Neurocognitive Outcome

The brain is a metabolic active organ with constant energy demands. Brain oxygen supply is secured via cerebral circulation. Brain tumor surgery is commonly associated with the tumor's underlying pathophysiology including brain swelling or edema. During craniotomy for brain tumor resection maintenance of cerebral hemodynamic stability is of paramount importance. …

18 - 80 years of age All Phase 4

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of ABBV-277 in Healthy Adult Participants

The objective of this study is to evaluate the safety, tolerability, immunogenicity and pharmacokinetics (PK ) properties following a single dose of ABBV-277 in healthy adult participants.

18 - 65 years of age All Phase 1

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