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Found 64,772 clinical trials
P Piotr Fudalej

Impacted Canine and Mixed-reality Technology - RCT

The goal of this clinical trial is to determine whether the use of HoloLens 2 mixed reality goggles for planning alignment of palatally impacted canine reduces: 1) treatment time and 2) the risk of complications compared to planning alignment of palatally impacted canine without HoloLens 2 goggles. Participants will have …

10 - 20 years of age All Phase N/A
D DAN LI, PhD.

Dual-targeting CLDN18.2 and PD-L1 CAR-T for Patients with CLDN18.2-positive Advanced Solid Tumors

Claudin18.2(CLDN18.2) is a kind of integrin membrane protein in the tight junction between epithelium and endothelium, which is highly expressed in many solid tumors, especially in gastric cancer and pancreatic cancer. The CLDN18.2/PD-L1 dual-targeting CAR-T will be investigated in patients with CLDN18.2-positive advance solid tumors.

18 - 75 years of age All Phase 1
S Sandrine BOUZON, CRA

Physical Activity Program for Reducing Blood Pressure in Sleep Apnea Patients With Resistant Hypertension

Investigators hypothesize that CPAP treatment for suppressing OSAS in combination with a physical activity program will optimize 24-hour blood pressure control in patients with OSA-related resistant hypertension.

18 - 80 years of age All Phase N/A
D Dr. Shahbaz Ahmed

Comparing Trypsin-Chymotrypsin and Naproxen Sodium for Post-endodontic Treatment Pain

This study aims to compare the pain reduction efficacy of Trypsin-Chymotrypsin and Naproxen sodium after root canal treatment in patients with symptomatic irreversible pulpitis. A lot of patients suffer greatly from post endodontic treatment pain and have a fear of dental treatments due to the pain. Patients refuse to go …

18 - 45 years of age All Phase 4
T Tianqi Zhu, MD PhD

Atomized Inhalation ICG for Treatment of Congenital Lung Malformations

To investigate the safety and effectiveness of preoperative aerosol inhalation ICG solution for thoracoscopic accurate resection of congenital lung malformations in children.

3 - 14 years of age All Phase N/A
A Alex Bowers

Reminder-cue Scanning Training for Homonymous Visual Field Loss

This study will evaluate a new approach to training people with visual field loss to scan when driving

16 years of age All Phase N/A
L Lucy J Abbott, Consultant Geriatrician

Promoting Increased Physical Activity in Hospitalised Older Adults

The PIVOT study will explore the feasibility of training volunteers to deliver exercise to hospitalised older adults to improve the health of older people and prevent deconditioning while in hospital. Loss of strength and mobility (i.e., deconditioning) is common in hospitalised older people and is associated with a decline in …

65 years of age All Phase N/A

Resin Modified Glass Ionomer Versus Self-Adhesive Resin Composite Restorative Systems

To evaluate and compare two-year clinical performance of commercially available resin modified glass ionomer cement, self-adhesive composite hybrid and self-adhesive flowable composite restorative materials for non-carious cervical lesions

30 - 60 years of age All Phase N/A
M Madeline Martinez Rivas, PhD

Smoking Cessation CM for Veterans With or at Risk for Cancer

Tobacco use among US Veterans poses significant health problems and challenges to their overall well-being. The aim of this project is to evaluate the effectiveness of a program called Contingency Management (CM) in helping Veterans quit smoking during lung cancer screening or cancer care at VA clinics. CM is a …

18 years of age All Phase N/A
E Elizabeth Hammond

Level Up! Adaptive Gaming for Children With Upper Limb Differences

The goal of this clinical trial is to test a new one-handed video game controller adapter to determine if it helps improve how video games are played and enjoyed in children with an upper limb difference on one side. The main questions it aims to answer are: Is performance improved …

7 - 17 years of age All Phase N/A

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