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T TULIN UNAL

Dual-Task Exercise Effects on Balance and Cognition by Physical Performance Level

This study aims to investigate the effects of dual-task exercises on balance and cognitive function in individuals with varying levels of physical performance. Dual-task training, which involves performing cognitive and motor activities simultaneously, has been shown to improve functional mobility, especially in older adults and patients with neurological conditions. However, …

20 - 50 years of age All Phase N/A
C Charlean Ketchens

Botensilimab Plus Balstilimab and Fasting Mimicking Diet Plus Vitamin C for Patients with KRAS-Mutant Metastatic Colorectal Cancer

This phase Ib trial tests the safety, side effects, and effectiveness of botensilimab, and balstilimab in combination with a fasting mimicking diet and high dose vitamin C in treating patients with KRAS-mutant metastatic colorectal cancer. Botensilimab and balstilimab are monoclonal antibodies that may interfere with the ability of tumor cells …

18 years of age All Phase 1
N Naoharu M., Naoharu Morimoto, MD

Investigate the Efficacy of Using NMN to Improve Embryo Development Capacity.

The objective of this study is to investigate the efficacy of NMN supplementation in enhancing embryo developmental capacity and improving IVF success rates in patients experiencing IVF failures.

32 - 42 years of age Female Phase N/A
M Momchilo Vuyisich, PhD

Viome Precision Nutritional Programs to Improve Clinical Outcomes for Mental Health Disorders

US residents who have mental health issues sign the informed consent form and are screened and enrolled for this study. Participants complete a survey upon enrollment and are randomized into one of two study arms. This study is direct to participant and will NOT utilize clinical sites.

25 - 75 years of age All Phase N/A
G Gabriele Capurso, PhD

Efficacy of PERT for PEI in Unresectable Pancreatic Cancer.

This will a be an open label, multicentre, randomized, controlled study in patients with unresectable pancreatic cancer, locally advanced or metastatic, with significant weight loss, and the tumour located in the head of the pancreas associated with dilated main pancreatic duct. Pancreatic Exocrine Replacement Therapy (PERT) in these patients will …

18 years of age All Phase 4
j jian zhang, phD

A Clinical Study of 9MW2821 (and PD-1 Inhibitor) in Locally Advanced or Metastatic Triple-Negative Breast Cancer

This study is a Phase 2, open-label,multicenter study designed to evaluate the efficacy and safety of 9MW2821monotherapy or combined with PD-1 inhibitor in locally advanced or metastatic Triple-Negative Breast Cancer.

18 - 75 years of age All Phase 2
J Julia V Semiletova

Carbon Suspension vs. Metallic Marker for Axillary Lymph Node Marking in Breast Cancer After Neoadjuvant Therapy

This single-center, randomized study aims to compare the intraoperative detection rates of axillary lymph nodes marked with carbon suspension versus metallic markers in breast cancer patients (T1-3N1M0) before neoadjuvant therapy. Primary endpoint: frequency of marked lymph node identification during surgery. Secondary endpoints: time from marking to surgery and quality of …

18 years of age Female Phase N/A
C Colin Berry, PhD

Heart Attack Blood Oxygen Therapy Trial

'Heart attack', known as acute ST-segment elevation myocardial infarction, is a leading cause of heart failure and death. A lack of blood and oxygen damages the heart muscle potentially causing heart failure and premature death. During the past 25 years, despite intensive research efforts, few, if any new medicines have …

18 years of age All Phase N/A
S Songul B Yentur

Ozone Therapy in Patients With Carpal Tunnel Syndrome

ESWT (Extracorporeal Shock Wave Therapy), which has been used in the treatment of musculoskeletal diseases in recent years, has come to the agenda as a new treatment method in Carpal Tunnel Syndrome. Although the effectiveness of ESWT, splinting and exercise applications in CTS patients is known in the literature, studies …

18 - 65 years of age All Phase N/A
G Guangyou Duan, MD

The Effect of Coenzyme Q10 in Preventing Pain After Thoracoscopic Surgery

This study aimed to assess the effectiveness of Coenzyme Q10 in preventing both acute and chronic pain following thoracoscopic surgery, with a focus on its potential benefits in reducing the incidence and severity of pain.

18 - 75 years of age All Phase 4

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