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Found 64,783 clinical trials
E Emine Can

Effects of Pilates Ball and Sacral Massage Applications on Labor Pain, Labor Duration and Childbirth Satisfaction

As researchers, we believe that Pilates ball and manual sacral massage applications can be easily and cost-free applied in maternity clinics in our country. For all these reasons, this study was planned as a randomized controlled study to evaluate the effects of Pilates ball and sacral massage applications in labor …

18 - 35 years of age Female Phase N/A
F Frederik Rønne Pachler, MD PhD

Ten Versus Fifteen Centimeter Pouch in IPAA Surgery

The aim of this randomized controlled trial is to compare outcome after construction of an ileal (J-shaped) reservoir of 10 versus 15 centimeters in primary ileal pouch-anal anastomosis surgery.

18 - 60 years of age All Phase N/A
A Ali Raza, DPT

Effects of Post-Isometric Relaxation Versus Static Stretching in Patients With Levator Scapulae Syndrome.

Group A will be treated with Postisometric relaxation technique and Group B will be treated with Static stretching technique. Postisometric relaxation will be performed with the frequency of 5 times, such that it includes (30 isometric contraction of the muscle to be stretched for 10 seconds, followed by rest period …

24 - 59 years of age All Phase N/A
J Josette Hartnett, MPH

Q Therapeutic System for Chronic Stroke Recovery

Evaluate the effectiveness of the Q Therapeutic (BQ 3.0) System for individuals with chronic stroke in improving upper extremity function as determined by change in functional outcome measures after 3-month treatment, including in-clinic and at-home sessions.

18 - 80 years of age All Phase N/A
Z Zhifeng Tian

Irinotecan Liposomes Combined With Bevacizumab in the Treatment of Recurrent Glioma

With the optimization of the dosage form of irinotecan, the replacement of ordinary irinotecan with irinotecan liposomes should improve the safety and the expected efficacy. Therefore, an exploratory study on the treatment progress of irinotecan liposomes combined with bevacizumab for recurrent brain glioma should be conducted. To evaluate the efficacy …

18 - 75 years of age All Phase 2

Study of MAR002 in Healthy Men

Evaluate the safety and tolerability of subcutaneous (SC) administration of MAR002 in healthy men

18 - 40 years of age Male Phase 1
C Charlotte Grégoire, PhD

Psychoneurological Symptom Cluster in Oncology

A psychoneurological symptom cluster is increasingly documented in oncology. It is composed of cancer-related fatigue, sleep difficulties, pain, emotional distress, and cognitive difficulties. These symptoms are linked by strong but complex relationships, and reinforce each other, negatively impacting patients' quality of life and survival. The configuration of this cluster (i.e., …

18 years of age All Phase N/A
B Barbara Sommerfeld, MSN, RN

Gamma Sensory Flicker for Parkinson's Disease Patients With Freezing of Gait

This study aims to answer the question: to assess the safety, and tolerability of gamma light in Parkinson's disease (PD) patients with freezing of gait (FOG). Parkinson's disease (PD) patients often experience a complex gait disorder known as Freezing of Gait (FOG). FOG is characterized by brief arrests of stepping …

50 - 80 years of age All Phase N/A
A Anissa Megzari

Optimizing the Care Pathway of Febrile Children Via Capillary C-reactive Protein Assay in Primary Care

Fever is the leading reason for outpatient consultations among children aged 2 to 9 years. The main concern in fever is severe bacterial infection, particularly for younger children. History and clinical examination do not always differentiate viral infections from bacterial infection. In 20% of febrile children, no infectious focus is …

3 - 15 years of age All Phase N/A
D Dominique BREMOND-GIGNAC

Metabolomics Analysis According to the Retinal Nerve Fiber Layer in Patients With NOHL Mutations (MétabOCT)

Leber hereditary optic neuropathy (LHON), due to mitochondrial DNA (mtDNA) mutations, is responsible for profound visual impairment. However, there is evidence that optic nerve damage begins before vision declines. There is no biomarker to determine when optic nerve damage begins before visual acuity decline occurs. We hope that the analysis …

18 - 60 years of age All Phase N/A

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