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Found 64,783 clinical trials
Y Yu Miao

Exploratory Study on the Treatment of Gout With Potassium Citrate Sustained-release Tablets

To evaluate whether alkalization has the effect of lowering uric acid and reducing gout flare and determine whether alkalization has a role in the prevention and treatment of urinary calculi in gout, the research participants were divided into the control group, the potassium citrate group and the sodium bicarbonate group. …

18 - 70 years of age All Phase 4
K Katrina Bouchard, Ph.D.

Cognitive-Behavioural Couple Therapy for Sexual Interest/Arousal Disorder

Sexual health is a fundamental aspect of quality of life; a satisfying sexual relationship is linked to better physical, psychological, and relationship health and well-being. In fact, people who maintain a satisfying, active sex life over time live longer than those who report lower sexual frequency and satisfaction. Yet problems …

18 years of age All Phase N/A
Ł Łukasz Kuncman, PhD

Radiotherapy Strategies for Use in Combined Treatment of Small-cell Lung Cancer

The purpose of this study is to evaluate the efficacy of radiotherapy as part of the combined treatment approach for patients diagnosed with histopathologically confirmed small cell lung cancer (SCLC) in the advanced stage of extensive disease (ED) who are undergoing chemo-immunotherapy. The planned study aims to assess the impact …

18 years of age All Phase N/A

Effect of Photobiomodulation to Reduce Post-operative Pain After Endodontic Surgery

The objective of this study will be to evaluate if photobiomodulation (FBM) can reduce postoperative pain in patients who will undergo endodontic surgery. For this randomized, controlled and double-blind clinical study, 34 patients without comorbidities who need endodontic surgery in the upper jaw (15 to 25 teeth) will be recruited. …

18 - 70 years of age All Phase N/A
L Lynsey Johnston

Investigating the Feasibility of Krill Oil Intervention to Improve Muscle Function in Adults With Long-term Conditions

This study will recruit 30 adults (men and women, aged 18 years and over) who will be randomly assigned to one of two groups in a 12-week double-blind pilot trial. Participants will receive either: Arm 1: Krill Oil group: 4 g/day of krill oil supplements (Superba™ Antarctic Krill Oil, 1000 …

18 years of age All Phase N/A
Q Qingqing Cai, MD

Sintilimab and Linperlisib Combination Treatment in Relapsed or Refractory Extranodal Natural Killer/T Cell Lymphoma

This is an open-label, phase Ib study evaluating the combination treatment of sintilimab and linperlisib in patients with relapsed or refractory extranodal natural killer/T-cell lymphoma (NKTCL).

18 years of age All Phase 1
A Alexs Matias, MS

Vascular Function and Oxidative Stress in Emergency Medical Responders

The goal of this clinical trial is to characterize blood vessel function and oxidative stress (a harmful condition that damages cells and tissues) in emergency medical technicians (EMTs). The main questions it aims to answer are: Does an overnight shift work in emergency medical technicians reduce blood vessel function and …

20 - 40 years of age All Phase N/A
R Ryan RHODES

All in the Family: Promoting Family Function Through Physical Activity

The goal of this trial is to find out whether adding identity-building and self-regulation training to basic healthy-living education helps families with inactive children (ages 6-12) become more cohesive and physically active. The main question it aims to answer is: Does the identity + self-regulation + education program improve family …

6 - 12 years of age All Phase N/A
I Igor Balaban, MD

Efficacy and Safety of Ranquilon in Patients With Anxiety Disorders Due to Neurasthenia and Adjustment Disorders

Study is to evaluate the efficacy and safety of the drug Ranquilon, 1 mg tablets, at a dosage of 6 mg/day compared to the drug Afobazole, 10 mg tablets, at a dosage of 30 mg/day for the treatment of patients with anxiety disorders due to neurasthenia and adjustment disorders.

18 - 70 years of age All Phase 4
J Jun Guo, Director

A Phase Ib Study of PRJ1-3024 for Treatment of Advanced or Metastatic Melanoma

This is a Phase Ib, open-label study to determine the safety and preliminary efficacy of PRJ1-3024 in China subjects with unresectable local advanced or metastatic melanoma

18 years of age All Phase 1/2

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