Advanced Filters
noise
Found 64,783 clinical trials
M Michael Rousek, MD

Indocyanine Green Fluorescence in Evaluation of Pancreatic Remnant Perfusion.

Main goal of this study is to evaluate the blood flow in a post resection pancreatic remnant after pancreaticoduodenectomy with use of indocyanine green fluorescence. If the hypothesis will be proven, evaluation of perfusion of the pancreatic remnant with indocyanine green could be used to estimate the increased risk of …

18 years of age All Phase N/A
M Max J Kurz, PhD

Neuromodulation of the Cortex and Spinal Cord

Specific Aim 1: To further quantify the difference in the sensorimotor cortical activity, spinal cord activity, and corticospinal coherence of persons with CP. Overall hypotheses: The sensorimotor cortical activity, spinal cord activity, and corticospinal coherence will be uncharacteristic in persons with CP when compared with neurotypical controls. Furthermore, the extent …

11 - 45 years of age All Phase N/A
D Dr Vinay Kumar, MDS

Comparative Evaluation of Indirect vs. Direct Pulp Capping in Deep Carious Mandibular Molars

Aim: To compare the outcome of indirect and direct pulp capping after partial or complete caries removal in deeply carious mature mandibular permanent molars with clinical signs indicative of moderate pulpitis. Objectives To evaluate the clinical and radiographic success of indirect pulp capping after partial caries removal in deeply carious …

18 years of age All Phase N/A
D Daxin Zhou, Prof

FreeFlow Percutaneous Atrial Septal Shunt for IPAH

The goal of this clinical trial is to explore the safety and efficacy of the FreeFlow percutaneous atrial septal shunt for treatment of idiopathic pulmonary arterial hypertension. The main questions it aims to answer are: Is the FreeFlow percutaneous atrial septal shunt safe to use in patients with idiopathic pulmonary …

18 - 70 years of age All Phase N/A
A Anne Louise Vandsø Svenningsen, MD

Bisphosphonate Prior to Parathyroidectomy in Primary Hyperparathyroidism

This study is a randomized, double-blinded, placebo-controlled trial investigating the effects of zoledronic acid (ZOL) versus placebo in patients with primary hyperparathyroidism (PHPT) undergoing parathyroidectomy (PTX). PHPT is a common endocrine disorder associated with hypercalcemia, reduced bone mineral density (BMD), increased fracture risk, renal calcifications, and cardiovascular complications. While PTX …

50 years of age All Phase 4
A Andrea Scribante, Associate Professor

Combined Use of Potassium Nitrate Gel and Diode Laser for Dentin Hypersensitivity

The aim of this clinical trial is to evaluate the efficacy of the combined use of a diode laser and a potassium nitrate-based desensitizing gel in reducing dentin hypersensitivity in adult patients. Patients who meet the eligibility criteria and for whom informed consent has been obtained will be enrolled and …

18 years of age All Phase N/A
R RAJINDER KR SHARMA, MDS

Impact of Bruxism in the Outcome of Subgingival Instrumentation for the Management of Stage 2 and Stage 3 Periodontitis.

Bruxism is a multifaceted phenomenon that has been associated with several factors mediated by the central nervous system3. Bruxism is an umbrella term grouping different motor phenomenon. 'Bruxism is a repetitive jaw-muscle activity characterized by clenching or grinding of the teeth and/or by bracing or thrusting of the mandible. Bruxism …

30 - 50 years of age All Phase N/A
N Na Li, MD

A Study on Application of Adjustable Headrest in Painless Curettage Surgery for Overweight and Obese Patients

The aim of this study is to observe the effect of adjustable headrests on ventilation function in overweight and obese patients through clinical experiments, and to explore the impact on the incidence of hypoxemia during painless curettage in overweight and obese patients. Participants will be randomly allocated to three groups: …

20 - 50 years of age Female Phase N/A
M Matheus Moreli Porceban, MD, PhD Student

Epidural Electrical Stimulation to Restore Standing and Walking in Patients With Chronic Paralysis Due to Spinal Cord Injury: A Study on Motor Recovery, Spasticity Reduction, and Quality of Life Improvement Through Neuromodulation and Intensive Rehabilitation

Spinal cord injury (SCI) is a major cause of morbidity and disability worldwide, significantly impacting patients' quality of life and functional independence. Despite advances in rehabilitation therapies, many individuals with SCI remain unable to stand or walk. Epidural electrical stimulation (EES) has emerged as a promising neuromodulation therapy to restore …

18 - 50 years of age All Phase N/A
R Rahel Askari

Determinants of Cardiorespiratory Fitness and Effects of HIIT in Patients With ANOCA Obstructive Coronary Artery Disease(ANOCA)

The main goal is to understand what causes reduced fitness in ANOCA and whether targeted exercise can help improve it. This study aims to better understand why patients with Angina and No Obstructive Coronary Artery Disease (ANOCA) have poor cardiorespiratory fitness and its effect on quality of life. Investigators also …

18 - 85 years of age All Phase N/A

Simplify language using AI