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Found 64,920 clinical trials
S Sichen C. Li

A Vaccine (Neoantigen-Targeted ppDC) for the Treatment of H3 G34-mutant Diffuse Hemispheric Glioma

This phase I trial tests the safety and side effects, and best dose of a vaccine (neoantigen-target ppDC) in treating patients with H3 G34-mutant diffuse hemispheric glioma. Vaccines made from the patient's own white blood cells and peptide-pulsed dendritic cells may help the body build an effective immune response to …

18 - 50 years of age All Phase 1
A Ayça ARACI, PhD

The Role of Focus Strategies on Pilates

Aims of the randomized controlled study is compare to the effects of external and internal focus strategies, commonly used in Pilates, on participants' reaction time and performance metrics. Conducted over an 8-week Pilates program at Alanya Alaaddin Keykubat University, we plan to include 25 participants in each focus group. Participants …

18 - 30 years of age All Phase N/A
X Xingshun Qi, MD

Efficacy and Safety of Local Glucocorticoids for the Treatment of Acute Radiation-Induced Intestinal Injury

Due to the increasing number and prolonged survival of malignant tumor patients treated with radiotherapy, the complication, such as acute radiation-induced intestinal injury, has become increasingly significant. Glucocorticoids may play a therapeutic role by regulating the inflammatory response in patients with acute radiation-induced intestinal injury. However, the conclusions of related …

18 years of age All Phase N/A
A Abdelrahman Mo omar, Master

Assessment of I-PRF Versus Nano MTA Combined with I-PRF Scaffold in Vital Pulp Therapy in Mature Mandibular First Molars

Assessment of I-PRF versus Nano Mineral trioxide aggregate Combined with I-PRF in pulpotomy in mature Mandibular First Molars

15 - 30 years of age All Phase N/A
C Carmen López de la Fuente, PhD

Motor Performance Improvement After Visual Rehabilitation

Acquired brain injury" refers to brain damage that impacts neurological processing, making daily activities challenging and often causing vision issues like binocular dysfunction, oculomotor problems, and visual field loss. In Spain, visual rehabilitation is limited, although it is more common in other countries. These patients generally need an interdisciplinary approach …

18 - 80 years of age All Phase N/A
J Jing Chen

Neoadjuvant Chemoimmunotherapy and Extrafascial Hysterectomy for IB2 Cervical Cancer

This study is an exploratory clinical trial to investigate the feasibility of neoadjuvant chemoimmunotherapy plus extrafascial hysterectomy and pelvic lymph node dissection in patients with stage IB2 (2018 FIGO) cervical cancer and to observe the response rate to treatment, adverse effects and complications, and to assess the survival rate of …

18 - 70 years of age Female Phase 2
s shimaa Bondok, PHD

Walking Program in Fatty Liver Children With Phenylketonuria

phenylketonuria (commonly known as PKU) is an inherited disorder that increases the levels of a substance called phenylalanine in the blood. PKU is usually associated with many metabolic complication including non-alcoholic fatty liver

9 - 12 years of age All Phase N/A

Exploratory Study of the Diagnostic Potential of an Innovative Thoracic Vibration Analysis Technique

Heart and lung disease are two major causes of hospitalisation and mortality in France (4-8). Together, these two diseases affect several million people in France, either acutely or chronically. They represent a major public health problem in social and economic terms. Diagnosis of these disorders is often delayed, with acute …

18 years of age All Phase N/A
M Mostafa M El Bukhari, MBBCH

Lignocaine vs Bupivacaine Infiltration for Postpartum Perineal Pain After Vaginal Delivery With Episiotomy in Primigravidae

In this study, we will compare the effect and safety of lignocaine versus bupivacaine infiltration for postpartum perineal pain after vaginal delivery with episiotomy in primigravidae.

18 - 40 years of age Female Phase N/A

Stylet Shape in Simulated Endotracheal Intubation by Medical Students

Endotracheal intubation is a life saving procedure where a tube is placed into a person's windpipe to help them to breathe. This is a study of which shape of tube would lead to improved success in this procedure.

21 years of age All Phase N/A

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