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Found 64,920 clinical trials
C Cathrein

Mid- or High-flex Rods Versus Low-flex Rods of SpineShape System IV for Treatment of Degenerative Lumbar Spine Diseases

The purpose of this multi-center, randomized, clinical study is to show that the treatment of degenerative lumbar spine with high- or mid-flex rods is not inferior to the treatment with low-flex rods in terms of clinical and safety-related results. The primary aim is to compare the reduction in back pain …

18 - 99 years of age All Phase N/A
G Gauthier Marion, MD

Contribution of Per Dialytic Physical Activity in Chronic Dialysis Patients

Dialysis patients have reduced walking capacity and an important risk of high blood pressure. These complications are associated with a decline in quality of life and increased mortality. The hypothesis of the study is to show that physical activity during the dialysis session in dialyzed patients has a benefit on …

18 years of age All Phase N/A
A Affiliated Hospital of Nantong University

Study of Sivelestat Sodium in OPCABG

The goal of this clinical trial is to learn if drug Sivelestat Sodium works to improve the prognosis of off-pump coronary artery bypass grafting (OPCABG) in adults. It will also learn about the safety of drug Sivelestat Sodium. The main questions it aims to answer are: Does drug Sivelestat Sodium …

18 - 75 years of age All Phase 2
A Angelo Scuteri, MD PhD

Comprehensive Approach to Reduce Elderly Functional Decline in Diabetes: the CARED Study

Importance. Conventionally, treatment goals for diabetic patients primarily target glycemic levels and traditional cardiovascular risk factors (blood pressure, lipids) control to reduce macro- and micro-vascular complications. More recently, the relevance of assessing functional status in older diabetic patients has emerged. A knowledge gap exists regarding the risk of functional dependency …

75 - 110 years of age All Phase N/A
C Cheng Lei, Chief physician

Study on the Effect and Mechanism of Lupatadine Fumarate in the Treatment of Allergic Rhinitis

In China, the prevalence of allergic rhinitis reaches 17.6% and is increasing year by year, seriously affecting the quality of life of patients. Some patients still cannot be effectively treated. So it is urgent to study the pathogenesis of AR and find new therapeutic targets. Lupatadine fumarate has the dual …

18 - 65 years of age All Phase N/A
S Susan Shur-Fen Gau, MD, PhD

Exploring the Gut-Brain-Behavior Axis With Biomarkers, Probiotic Efficacy, and Artificial Intelligence Algorithms

This groundbreaking human study on the ASD microbiome includes probiotic clinical trials, investigation of treatment biomarkers, machine learning/deep learning platform development for ASD classification and prediction, and identification of diagnostic biomarkers. Upon completion, the investigators anticipate publishing at least 12 SCI papers and/or patents and establishing an auxiliary diagnosis platform …

4 - 15 years of age All Phase N/A
R Ralph Ortiz, DO

Sustained Acoustic Medicine for Symptomatic Treatment of Knee Pain Related to Osteoarthritis

The purpose of this study is to assess the ability of long-duration low intensity therapeutic ultrasound (LITUS) to alleviate knee Osteoarthritis pain over a 24-week period. The primary objective of this study is to evaluate the analgesic effect of LITUS in subjects suffering from knee Osteoarthritis pain. Secondary objectives are …

50 - 85 years of age All Phase 2
K Karen Basen-Engquist, MD

Active Living After Cancer: Implementation Within Be Well Acres Homes

The goal of this research study is to learn more about a physical activity program adapted for cancer survivors.

18 years of age All Phase N/A
M Martin Kronschläger, PhD

Visual Performance of an Extended Depth of Focus IOL in an Emmetropic or Monovision Modality

Comparison of the visual performance of a refractive extended depth of focus intraocular lens in an emmetropic or monovision modality

21 - 105 years of age All Phase N/A

Fistura® Procedure for the Treatment of Complex Anal Fistulas

This study aims to evaluate the healing rate of complex fistulas using radiofrequency (Fistura® procedure), in a prospective, interventional, monocenter, single-arm design.

18 years of age All Phase N/A

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