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Found 64,783 clinical trials
A Audrey Carrillo

Working Memory Training for People Aging with HIV

The present study investigates the feasibility of working memory training in people aging with HIV (PAWHIV). In a cross-over design this stage 1 feasibility trial, will evaluate acceptability, and estimate possible effect sizes related to working memory training by examining potential differential effects in PAWHIV and those aging without HIV. …

50 - 85 years of age All Phase N/A
Y Yi Xia

Fixed-Duration Zanubrutinib, Bendamustine, and Obinutuzumab (ZBG) in Treatment-Naïve Advanced Stage Follicular Lymphoma

This study investigates a fixed-duration regimen of zanubrutinib, bendamustine, and obinutuzumab (ZBG) in the treatment of treatment-naïve patients with advanced-stage follicular lymphoma. Patients will receive combination therapy with zanubrutinib, bendamustine, and obinutuzumab over 6 cycles, with each cycle lasting 28 days. The specific dosing schedule is as follows: Bendamustine 70 …

18 - 75 years of age All Phase N/A
U Ulrich Stangier, Professor

Process-based Therapy for Difficult-to-treat Anxiety Disorders and Depression

The aim of this study is to test the relative efficacy of Process-based Therapy compared to traditional CBT delivered in routine practice (r-CBT) for difficult-to-treat anxiety disorders and depression.

18 - 65 years of age All Phase N/A
K Kıvan Çevik Kaya

The Effect of Progressive Relaxation Exercises by Nursing Students Before Clinical Practice

Aim: We conducted this randomized controlled study to determine the effect of Progressive Relaxation Exercises practiced by first year nursing students before clinical practice on their perceptions of stress, psychological resilience and meaning of life. Background: Progressive Relaxation Exercises has a positive effect on the person's mental/general health, life satisfaction …

18 - 45 years of age All Phase N/A
M Maggie Lit, MN

A Smart Self-Management Support Programme (3S) to Improve Quality of Life in Lung Cancer Patients

Lung cancers patients often experience multiple symptoms (e.g. fatigue, dyspnea, distress, depression, sleep disturbance). The current study attempts to explore the efficacy of the Smart Self-Management Support Programme (3S) in improving quality of life of patients using self-management support programme with mobile devices.

18 - 100 years of age All Phase N/A
F Fred Hutch Intake

Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer

This phase I/II trial tests the safety and effectiveness of cell therapy (STEAP1 CART) with enzalutamide in treating patients with prostate cancer that continues to grow despite surgical or medical treatments to block androgen production (castration-resistant) and that has spread from where it first started (the prostate) to other places …

18 years of age Male Phase 1/2
D Doaa G Abdelbaset, MSc

Efficacy and Safety of Topical Vitamin D Analogue in Treatment of Female Pattern Hair Loss

The trial aims to study efficay of topical vitamin D analogue in treatment of female pattern hair loss cases

15 - 60 years of age Female Phase 1/2
J Justyna Szklarzewicz, MSc

A Study of Probiotics in IgA Nephropathy

IgA nephropathy (IgAN) occurs when a specific form of the IgA antibody lodges on the kidneys and causes damage, which may lead to kidney failure. This form of IgA is likely to come from the gut and the upper airways. Recent studies have shown that the bacteria that live in …

18 years of age All Phase N/A
A Anna Schandl, Docent

Pilot Study of a Multidisciplinary Intervention in ICU Survivors At Risk for Psychological or Physical Morbidity

Pilot study of the feasibility and utility of an early, in-hospital multidisciplinary intervention in ICU survivors at risk for psychological and physical problems post-ICU stay

18 years of age All Phase N/A
J Jing He

BCMA-CD19 CAR-T Therapy for Refractory Autoimmune Diseases

The objective of this study is to evaluate the efficacy and safety of BCMA/CD19 chimeric antigen receptor (CAR)-modified T cells in the treatment of autoimmune diseases.

18 - 65 years of age All Phase 2

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