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Found 44 clinical trials
A Anki MIU, MSc

CUHK Brain Health Longitudinal Study

The goal of this study is to develop a large longitudinal cohort of individuals diagnosed with or at high risk for brain diseases (both neurological and psychiatric in nature), in order to identify risk factors that contribute to neurological and psychiatric diseases over time. The investigators seek to capture relevant …

18 years of age All Phase N/A
S SAMIERI Cécilia, Dr

Biobank and Brain Health in Bordeaux.

B cube is a new generation cohort to study the determinants and natural history of brain aging, using molecular epidemiology, in a representative sample (N=2000) of the general population from the age of 55 (the approximate age of onset of the first cognitive disorders and a target population particularly receptive …

55 - 80 years of age All Phase N/A
S Stephanie Wilbrand, PhD

Brain Health Oneida

The purpose of this observational study is to better understand the relationship between stroke risk factors and brain MRI measures in the Native American population. Participants will undergo: Carotid ultrasound Magnetic resonance imaging (MRI) Cognitive testing

55 - 90 years of age All Phase N/A
J Jane Sharpless, MS

University of Pittsburgh Brain Health Initiative

This project will define the prevalence of brain health (i.e., normal cognitive, neuromotor, behavioral function) in living professional football retirees and group-matched controls through a comprehensive assessment of clinical, neuroimaging, and biomarker measures.

29 - 59 years of age Male Phase N/A
K Kathleen Van Dyk

Brain Health in Breast Cancer Survivors

Endocrine therapy (ET) is widely used to treat hormone receptor positive breast cancer and prevent recurrence by downregulating estrogen function. However, ETs readily cross the blood brain barrier and interfere with the action of estrogen in the brain. Estrogen supports cognition and menopausal status is closely linked to cognitive health …

35 - 65 years of age Female Phase N/A
A Ava Grier, BSc

Brain Health and Exercise in Schizophrenia

To determine the effects of aerobic exercise on hippocampal volumes and severity of psychotic symptoms in a population of psychosis patients compared to healthy age/gender matched volunteers. Psychosis patients often suffer from a number of cognitive difficulties, including poor memory function, poor problem-solving capacity and difficulties with attention and concentration. …

19 - 45 years of age All Phase N/A
L Laura Thomas, MSc

Respiratory Support and Brain Health in Preterm Infants

Premature babies often require breathing support during their neonatal intensive care unit stay. This is because their lungs are not fully developed to perform the work of breathing on their own. Although breathing support can be provided via a breathing tube, it is preferable to provide breathing support non-invasively from …

3 years of age All Phase N/A
P Pauline Kwan, MSoSc

The Impact of Excessive Dietary Sodium on Brain Health

Sporadic cerebral small vessel disease (CSVD) is not only the most common subtype of vascular dementia, in recent multi-center study showed that sporadic CSVD harbors in a third of Alzheimer's disease (AD) patients in 9 Asian regions. The CSVD increases the severity of cognitive impairment in these patients and has …

55 - 80 years of age All Phase N/A

Physical Activity, Sleep and Brain Health Based on the Glymphatic System

This study is aiming to analyze the impact of physical activity on neurohydrodynamics and glymphatic activity on young adults. This study is designed as a multicenter descriptive observational study with information collection at two different times: before performing a short exercise routine and during its performance using a wearable wireless …

18 - 40 years of age All Phase N/A

The Link Between Physical Activity and Brain Health in Healthy Adults

The goal of this observational study is to investigate the cross-sectional relationship between physical activity and brain health from a multiscale approach (neuropsychology, neuroimaging, peripheral biomarkers and genetics) in former athletes and sedentary individuals. The main question it aims to answer is: Do former athletes have better brain structure than …

40 - 75 years of age All Phase N/A

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