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Found 64,783 clinical trials
R Ryan Callahan, MD

Calculating Wall Shear Stress in Infant Pulmonary Veins

The purpose of this study is to better understand pediatric pulmonary vein stenosis (PVS), which is the narrowing of blood vessels that connect the lungs to the heart. PVS is a life-threatening disease without a clear cause. The investigators think patients who develop PVS have an increased Wall Shear Stress …

- 18 years of age All Phase 1
K Kanokkarn Wongmayurachat

Intravenous TNK vs TPA for AIS Treatment on MSU,a Prospective Multicenter RCT

Acute ischemic stroke is one of the devastating diseases that increase hospitalization, disabilities, and deaths worldwide. Current treatment with intravenous thrombolytic agent can help reduce disabilities and improve quality of life. Intravenous Alteplase is proven benefit and now used as the first-line drug for acute ischemic stroke with symptom onset …

18 years of age All Phase 4
G Gabriela de Vasconcelos, PhD

Effectiveness of Manual and Instrumental Myofascial Release in Chronic Low Back Pain and the Posture of Practitioners CrossFit®

Background: Chronic low back pain (LBP) can lead to major functional disabilities and force people to take time off work, sports or leisure activities. Regular physical exercise is an important ally in reducing the risk factors for most diseases, and CrossFit® is one of the modalities that has been gaining …

18 - 59 years of age All Phase N/A
Y Yin HU, PhD

Orthokeratology and 0.01% Atropine Sequential Treatment for Myopia Control

The purpose of this multicenter randomized clinical trial is to evaluate the myopia control effect of orthokeratology and 0.01% atropine sequential treatment in children and adolescents, as compared to continuous treatment with orthokeratology.

8 - 15 years of age All Phase N/A

A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's Dementia

This is a multicenter, randomized, double-blind, placebo-controlled, flexible-dose study of the efficacy, safety, and tolerability of ITI-1284 in patients with agitation associated with Alzheimer's dementia

55 years of age All Phase 2

An Study to Evaluate Safety and Tolerability of OA-SYS in Subjects with Moderate to Severe Osteoarthritis of the Knee Joint

This study is being conducted to evaluate the safety and tolerability of OA-SYS in patients with moderate to severe OA of the knee joint.

35 - 75 years of age All Phase 2
M Mai N Ageez, MD

Local vs Systemic Methotrexate in Management of Uterine Ectopic Pregnancy

This study aims to compare local and systemic methotrexate in the management of uterine ectopic pregnancy regarding the duration of beta human chorionic gonadotropin (hCG) clearance and need for further management options.

20 - 40 years of age Female Phase N/A
E Emil Hagström, MD, PHD

Effects of a Healthy Nordic Diet on Atherosclerosis in Patients with Coronary Heart Disease

Diet can play a key role in atherosclerosis and coronary heart disease (CHD), but little interventional data exists, and the mediators of possible anti-atherosclerotic effects of diet are unclear. The investigators will investigate if a healthy Nordic diet (HND) reduces plaque volume, coronary artery calcification (CAC), and plaque inflammation (FAI) …

50 - 80 years of age All Phase N/A

The Effect of Oketani Breast Massage on Breastfeeding

This study aims to determine the effects of Oketani breast massage on breastfeeding success, breastfeeding self-efficacy and satisfaction of primiparous mothers.

18 - 45 years of age Female Phase N/A
J Jiwen Wang, Doctor

Evaluation of the Safety, Tolerability, and Efficacy of LE051 in Patients With Duchenne Muscular Dystrophy

The purpose of this study is to evaluate the safety, tolerability, and efficacy of LE051 intravenous therapy in DMD patients treated with exon 51 skipping therapy.

4 - 8 years of age Male Phase N/A

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