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Found 64,783 clinical trials
M Miriam Goldberg

Integrative Therapies in Multiple Myeloma

Multiple myeloma is a hematologic malignancy that can cause anemia, renal failure, bone disease, and hypercalcemia. Today, myeloma is considered a chronic disease and most patients will receive ongoing biological treatments. As a result, this disease causes a number of symptoms related to the disease itself or its treatment, which …

18 years of age All Phase N/A
A Alexandrine VIDAL, MD

Amoxicillin Alone Versus Amoxicillin/Clavulanate for Community-acquired Pneumonia in Patients Aged 65 Years or Older, and Hospitalized in a Non-intensive Care Unit Ward

Reduce inappropriate antibiotic use is a priority of public health agencies. Community-acquired pneumonia (CAP) is one of the most important indications for antibiotic prescriptions. In the majority of the studies of CAP, there is a large proportion of cases with no pathogen identified. Thus, the choice of the empirical antibiotic …

65 years of age All Phase 3

Effects of Ballistic Six Exercises With and Without Blood Flow Restriction in Cricket Players

Cricket is not only a widely played team sport, but it also involves intricate skills that are honed over time, especially in bowling. One of the key concerns for bowlers is the risk of developing shoulder injuries due to imbalances between the agonist and antagonist muscle groups. To address this, …

18 - 25 years of age Male Phase N/A
P Paul J Turek, MD

Spermatogonial Differentiation Via Testicular Organoid

Purpose This clinical trial aims to explore the potential for human sperm production in vitro by sustaining a laboratory-cultured adult testicular environment. It also seeks to identify genetic factors contributing to human sterility and failed spermatogenesis. The study's primary objectives include: Identifying genomic markers associated with sterility and failed spermatogenesis. …

18 - 60 years of age Male Phase 1/2

PNF Technique on Iliopsoas and Hamstring Muscle on Chronic Low Back Pain

The aim of the study to evaluate the effects of PNF in terms of decreasing low back pain, increasing range of motion and improving flexibility of the hamstrings and iliopsoas. Their association in LBP can be found through studies and my study based on this point will show whether targeting …

15 - 40 years of age All Phase N/A
W Wajeeha Mahjabeen, MBBS

Vitamin D Supplementation in Acne

The goal of this clinical trial is to compare in acne vulgaris patients. The main question it aims to answer is: • To assess the therapeutic benefit of vitamin D supplement in acne vulgaris treatment, following a 2-month treatment regimen that includes vitamin D supplementation compared to conventional (systemic azithromycin …

13 - 40 years of age All Phase N/A
H Hua Zhong

Intrathecal Injection Pemetrexed And Bevacizumab in Patients With Leptomeningeal Metastases in NSCLC

This is a prospective, single-arm, phase Ia clinical study, which was designed to evaluate the efficacy and safety of Pemetrexed Combined With Bevacizumab Intrathecal Injection in Patients With Leptomeningeal Metastases in NSCLC.

18 years of age All Phase 1
Z Z-Hye Lee, MD

Pilot Study of Management of Facial Paralysis in the Oncologic Patient: Nerve Transfer Techniques to Improve Facial Function and Quality of Life

The goal of this research study is to measure changes in patients' quality of life after surgeries that affect the facial nerve, including nerve transfer as treatment for facial paralysis.

18 years of age All Phase N/A
H Haitao Zhao, MD

Combination of Cardonizumab Injection and TKI Second Line Therapy for Advanced Hepatocellular Cancer

The goal of this clinical trial is to evaluate the efficacy and safety of cardonilizumab injection combined with TKI in second-line treatment of advanced hepatocellular carcinoma. The main questions it aims to answer are: Objective response rate (ORR) for evaluation Disease Control Rate (DCR); Duration of relief (DoR); Progression free …

18 - 75 years of age All Phase 1
S Sergey Motov, MD

Virtual Reality and Standard Care vs. Standard Care Alone for Acute MSK Pain in Geriatric ED Patients

The proposed Virtual Reality as an Adjunct to Pain Management for Geriatric Patients in the ED (VRAP-ED) project will take place in the Emergency Medicine Department at Maimonides Medical Center. It seeks to enhance the analgesic practices for geriatric patients with acute painful conditions in the emergency setting. Although virtual …

65 - 120 years of age All Phase N/A

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