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Found 64,783 clinical trials
M Momen A Atieh, BDS, MSc, DClinDent, PhD, FPFA

Single Implant Crowns Supported by Narrow or Standard Diameter Implants in Molar Sites

Standard dental implants require sufficient bone and spacing, which may not be available in all patients. To address these limitations, narrow diameter implants (≤3.5 mm) have been introduced as a less invasive alternative, especially useful for medically compromised patients or those avoiding bone grafts. However, narrow implants made of pure …

18 years of age All Phase N/A
J John Burns, PhD

Comparing Single-Session Therapies for Chronic Pain

Many people in the US suffer from chronic pain. Often times, individuals who have chronic pain also feel depressed, anxious, or hopeless, which can worsen pain. Psychologists, therefore, have developed several treatments to help people with chronic pain. These psychological treatments differ. The most common treatment is Cognitive Behavioral Therapy …

18 years of age All Phase N/A
E Enid Keseko

Researching Engagement With Educational Lifestyle Content

The goal of this study is to examine how different types of health messages affect people's self efficacy for healthy eating and diet quality. Eligible adult participants with overweight/obesity will be randomized into one of two groups: the intervention group, which will engage with audio-visual messages per week for four …

18 - 65 years of age All Phase N/A
E Erin Kasson

Testing the Feasibility and Acceptability of Social Media and Digital Therapeutics to Decrease Vaping Behaviors

Use of vaping products (e.g., electronic nicotine delivery systems, e-cigarettes) has been increasing rapidly, particularly among teens and young adults. With limited information on the long-term effects of vaping products, health information about vaping has been somewhat unclear in regards to associated health risks. Teens and young adults may be …

15 - 25 years of age All Phase 1
h hua zhang

Afatinib Combined With Chemotherapy as Conversion Therapy in Unresectable EGFR Sensitive Mutation-positive Stage III NSCLC

This is a phase II, single-arm study to evaluate the efficacy and safety of Afatinib plus chemotherapy as conversion treatment in patients with unresectable EGFR sensitive mutation-positive stage III non-small cell lung cancer.

18 years of age All Phase 2
W William W Stoops, Ph.D.

Methamphetamine and Troriluzole

This will be a human laboratory study evaluating the influence of troriluzole treatment on the effects of methamphetamine.

18 - 55 years of age All Phase N/A
A Amr Wahdan

Adding Dexmedetomidine to Mannitol to Attenuate the Increase of Intracranial Pressure

Dexmedetomidine is a potent alpha-2 adrenergic receptor agonist. In addition, dexmedetomidine-induced stimulation of the postsynaptic alpha-2 adrenergic receptor on the cerebral blood vessels can cause cerebral vasoconstriction and decrease cerebral blood flow

40 - 70 years of age All Phase 2/3
E Emad Tawfeik

Evaluation of Retrograde Intra Renal Surgery in the T-tilted Position

To evaluate the effect of the T-tilted position on the stone-free rate compared to the standard lithotomy position in retrograde intrarenal surgeries. Common positions include the Trendelenburg position, where the patient is tilted head-down to help gravity move stones from the upper calyces to the renal pelvis, and the modified …

16 years of age All Phase N/A
G Gabriela Buccini

Nurturing Care Family Navigator

The goal of this pilot randomized controlled trial is to determine whether a 6-month behavioral health intervention with a Nurturing Care Family Navigator (NCFN) improves levels of food security among postpartum low-income Medicaid or uninsured women identified as having very low or low food security in the past 12 months. …

18 years of age Female Phase N/A
P Pierre-Emmanuel Bouet, MD

Impact of Time on Sexual Function (FSFI® Score) After Hysterectomy

In France, more than 62 000 hysterectomies are performed each year. Female sexual function is the result of multiple psychological, social and physiological factors. There is no information in the current literature about the optimum time between the surgery and the sexual relation resumption. The primary outcome is to assess …

18 years of age Female Phase N/A

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