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Found 65,447 clinical trials
Z Zeynep ARABACI

Evaluation of the Psychoeducation Program Given to the Elderly Living Alone at Home in Terms of Some Parameters

It was aimed to evaluate the effectiveness of the psychoeducation program given to the elderly living alone at home. In this context, the psychoeducation given was planned to evaluate the effect of the psychological well-being, self-integration and coping levels of the elderly.

65 - 95 years of age All Phase N/A
D David McCall

A Phase I Study Investigating the Combination of the Ziftomenib, Venetoclax and Azacitidine in Pediatric Relapsed and Refractory Acute Leukemias

To find the highest safe dose of ziftomenib that can be combined with venetoclax and azacitidine in pediatric participants with acute leukemia that has certain types of genetic mutations (changes).

2 - 21 years of age All Phase 1
B Baozhong Li

Treating Nectin-4-positive Advanced Breast Cancer with XKDCT293 (Nectin-4-CAR-T)

A single-center, single-arm, dose-escalation exploratory clinical trial of the safety, efficacy, and pharmacokinetics of XKDCT 293 (Nectin-4-CAR-T) in Nectin-4-positive advanced breast cancer

18 - 75 years of age All Phase 1
Ü Ülkü yılmaz, PHD

The Effect of Elderly Care Training Given to Nursing Students on Ageism

geism is a multidimensional term that includes different attitudes, prejudices, behaviors and actions shown to a person simply because of his or her age. Today, in most societies in the world, elderly individuals are discriminated against. This discrimination stems from the negative attitudes of family members and society in general …

18 years of age All Phase N/A
C Chaelin Lee, BSPT

Feasibility and Safety of Digital Rehab Platform for Bedridden Patients

Study Title Rehabilitation Program for Bedridden Patients Using Digital Devices Study Purpose This study aims to evaluate the effectiveness of a rehabilitation program using digital devices and apps for bedridden patients in a hospital setting. The goal is to determine if digital rehabilitation can help improve physical function and contribute …

19 years of age All Phase N/A

A Trial in Healthy Adult Participants to Evaluate the Safety, Tolerability, and Behavior in the Body of TBD11

This is a randomized, double-blind, placebo controlled First in human (FIH) trial of TBD11, administered to healthy adults. The trial will be conducted in two parts. Part 1 will consist of single ascending dose (SAD) and Food effect (FE) cohorts, and Part 2 will consist of multiple ascending dose (MAD) …

19 - 55 years of age All Phase 1
P Paul A Nuzzo, M.A.

Cannabis and Opioid Use Disorder

This study plans to enroll participants with opioid use disorder who are not currently seeking treatment to assess the effects of cannabis on opioid withdrawal and other related outcomes.

18 - 55 years of age All Phase 1
J Jason M Wilken, PT, PhD

CMT Gait, Mobility, Balance - AOFAS Grant

The overall objective of the proposed research is to begin to better understand the potential benefits and limitations of ankle -foot orthosis (AFO) use in the context of mobility and balance during gait for individuals with Charcot-Marie-Tooth disease (CMT). These benefits will be studied in comparison to those offered by …

25 - 55 years of age All Phase N/A
X Xue Yang, PhD

An Internet-based Self-help Intervention to Improve Common Mental Health Problems Among Medical Professionals

This randomized controlled trial (RCT) aims to evaluate the effectiveness of an internet-based guided self-help intervention developed based on Problem Solving Therapy, a transdiagnostic low-intensity intervention recommended by the World Health Organization, in improving medical professionals' mental health.

18 - 60 years of age All Phase N/A
D David SC Hui, MD

Trial of Reduced Alteplase Dose for Parapneumonic Effusion (TRAPPE)

Objectives: A pilot study to compare the therapeutic and safety profiles between low(2.5mg) and standard(10mg) doses of intrapleural tissue plasminogen activator(tPA) in uncontrolled pleural infection. The study design will be tested for its trialability. Hypothesis: 2.5mg tPA has comparable therapeutic efficacy and less bleeding complications to 10mg tPA. Design and …

18 years of age All Phase 2/3

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