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P PAYOUX Pierre

Validation and Implementation of 3T MRI Research Protocols

The Philips 3T imager installed on the Pavillon Baudot site is an imager dedicated solely to research. It is not located in hospital premises but in INSERM premises for which an authorization for biomedical research has been granted. This equipment is part of the Technical Platform of the UMR 1214 …

18 years of age All Phase N/A
W Weihua Zhao, Phd

taVNS Effects on Fear Ratings in Naturalistic Context

During the fear rating task, 70 participants viewed a 600-second horror movie while continuously rating their subjective fear intensity (0-100 scale) every 0.51 seconds (1,170 total ratings). Functional near-infrared spectroscopy (fNIRS) data were simultaneously recorded using the NIRSIT LITE system to monitor cortical hemodynamic responses.

18 - 30 years of age All Phase 1
T Tongji Hospital, Huazhong University of Science and Technology

Proximal Gastrectomy Vs Total Gastrectomy in Locally Advanced Upper Gastric Cancer After Neoadjuvant Therapy

We plan to evaluate the efficacy and safety of proximal gastric vs. total gastric radical resection after SOX combined with anti-PD-1 neoadjuvant therapy in locally advanced upper gastric cancer

18 - 75 years of age All Phase 4
M Mohamed Hussiny

Efficacy and Safety of Tamsulosin for Children with Posterior Urethral Valve.

To determine whether there is a role for Tamsulosin, A Selective Alpha-1 Adrenergic Blocker, as therapy in children with Posterior Urethral Valve post valve ablation , and whether there are side effects involved.

- 12 years of age Male Phase 3
L Liangkun Ma

Managing Pregnancy Pain With Baduanjin Exercise

This is a randomized controlled trial studying whether a 12-week Baduanjin exercise program (a traditional Chinese mind-body exercise) can reduce low back pain and improve quality of life in pregnant women.

18 - 45 years of age Female Phase N/A

Correlation Between Postoperative Pain and Apical Extrusion of Different Irrigation Activation Techniques

The aim of this clinical trial is : To evaluate effect of different techniques of irrigant activation: LASER activation sonic activation ultrasonic activation passive needle irrigation On Postoperative pain in vital teeth (Randomized controlled trial) Amount of apical extrusion (In vitro study) Participants will describe their preoperative pain and postoperative …

18 - 50 years of age All Phase N/A
c carlalberta verna

The Use of a Pacifier to Correct Malocclusions in Young Children

The aim of the study is to investigate the effect of a pacifier (102 Medical Pacifier, Curaprox, Switzerland) on malocclusions like posterior crossbite, anterior open bite, larger overjet and tongue dysfunction in young children.

2 - 5 years of age All Phase N/A
T Tianshu Liu

A Study of HDM2012 in Patients With Advanced Solid Tumor

This is a first-in-human (FIH) study to evaluate the safety and preliminary efficacy of experimental drug HDM2012 in patients with advanced solid tumors.

18 - 75 years of age All Phase 1
C Chloé Melchior, MD, PhD, PI

Effectiveness of a Dietary Supplement in Irritable Bowel Syndrome

Irritable bowel syndrome (IBS) affects around 5% of the general population and remains a daily problem in clinicians' practices, with inconsistent efficacy of treatments despite patients' high expectations. Intestinal hyperpermeability and visceral hypersensitivity are the two major components of IBS, and both can disrupt gastrointestinal function and ultimately impair patients' …

18 - 75 years of age All Phase 2

A Study to Compare and Evaluate the Pharmacokinetic Characteristics and the Safety Between Administration of BR2021 and BR2021-1

The purpose of this clinical study is to compare and evaluate the pharmacokinetic characteristics and the safety between administration of BR2021 and BR2021-1 in patients with metastatic adenocarcinoma of the pancreas

19 - 74 years of age All Phase 1

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