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Found 64,783 clinical trials
C Christian Molnar, Doctor

RSV Immunogenicity Study in the Elderly (RISE)

Respiratory syncytial virus (RSV) is a common cause of respiratory tract infections leading to hospitalizations in infants and in elderly. Arexvy is an approved vaccine for the prevention of RSV infection, however, data on its efficacy in individuals aged 80 years and older remain limited. This study aims to evaluate …

60 years of age All Phase 3

Mitral Annular Repair With the CathHELIX™ Transcatheter System in Subjects With FMR

Patients with functional mitral regurgitation classified as moderate to severe (3+) or severe (4+) that are symptomatic (NYHA Class II-IV) will be evaluated for treatment using the CathHELIX Transcatheter Mitral Annuloplasty System.

18 years of age All Phase N/A
G Gezhi Xu, PhD

An Clinical Study Evaluating the Safety, Tolerability, and efficAcy of HG005 in StaRgardT Disease

Stargardt disease type 1 (STGD1) is a rare genetic eye condition that causes progressive vision loss, often beginning in childhood or adolescence. It is the most common form of inherited macular degeneration and can lead to legal blindness. STGD1 is caused by mutations in the ABCA4 gene, which normally helps …

6 - 17 years of age All Phase N/A
M Melissa Felt

AI Assisted Personalized Legacy Program (Reflections: My Story) for Patients With Serious Illness

The purpose of this study is to determine if it is feasible and acceptable to recruit for and deliver the AI Assisted Personalized Legacy Program intervention to patients with serious illness.

18 years of age All Phase N/A
F Feng Wang, phD

Safety and Efficacy of SHR2554 Combined With Other Antitumor Therapies in Gastric or Gastro-oesophageal Junction Adenocarcinoma

This is a multicenter, phase 2, open label study to evaluate safety, tolerability and efficacy of SHR2554 combined with other anti-tumor treatments in patients with advanced or metastatic gastric or gastroesophageal junction adenocarcinoma.

18 - 75 years of age All Phase 2
E EMEL SALCAN

Meditation in Early Labor: Impact on Self-Efficacy and Childbirth Fear in First-Time Mothers

Aim-Introduction: The feeling of uncertainty about what will happen during labor, and the mother's perception of inadequacy regarding childbirth, can lead to anxiety and stress in some pregnant women, resulting in fear of childbirth and avoidance behaviors. This study was conducted to examine whether there are significant differences in childbirth …

18 years of age Female Phase N/A
C Clinical Cancer Research Unit

PQ203 in Advanced Malignant Tumors Including Triple Negative Breast Cancer

The primary purposes of this study are to determine the safety and tolerability of PQ203 in patients with advanced solid tumors including triple negative breast cancer (TNBC), and to determine a recommended Phase 2 dose level for future studies in TNBC.

18 years of age All Phase 1
A Aviva Ogbolosingha

Trans-radial Superior Rectal Artery Embolisation for Haemorrhoids

Endovascular embolisation is already a common procedure for bleeding haemorrhoids in the acute setting, where surgical options are not possible or have been exhausted. This pilot study aims to add to the small body of evidence that transarterial embolisation of symptomatic haemorrhoids is also safe and effective in the elective …

18 years of age All Phase N/A
C Cansu Akdag Topal

EFFECT OF GUIDED IMAGERY ON PREMENSIVE SYNDROME IN UNIVERSITY STUDENTS

Premenstrual Syndrome (PMS) is typically defined as a condition characterized by physical, behavioral, and emotional symptoms that typically appear at the end of the luteal phase of the menstrual cycle, occur 7-10 days before menstruation, and disappear at the onset of menstruation or shortly thereafter. The symptoms of PMS include …

years of age Female Phase N/A
A Aruba Saeed

LSVT Big and Dual Task Training in Cognitive Impaired Patients

The goal of this study ifs to determine the comparative effects of Lee Silverman voice treatment Big and dual task training on balance, cognition and functional mobility in older adults with cognitive impairment. Perform LSVT big four times in a week for about 4 months. Perform dual task training four …

65 years of age All Phase N/A

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