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Found 64,783 clinical trials
N Ning Li

A Study of CSCJC3456 in Patients With Advanced Malignant Tumors

This study is a multicenter, open phase I clinical study of dose escalation, cohort expansion study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary efficacy of CSCJC3456 in patients with advanced malignant solid tumors.

18 - 75 years of age All Phase 1
Y Yu Cao, Doctor

HS-10542 Study in Healthy Participants

This is a randomized, double-blind, placebo-controlled, dose escalation phase I clinical study to evaluate the safety, tolerability, pharmacokinetics, and the food effect on the pharmacokinetics of HS-10542 in healthy participants.

18 - 64 years of age All Phase 1
U Uta Solecke, Dr.

An Investigation to Evaluate Wearing Properties of Three Different Investigational Devices

This clinical investigation will assess the self-adhesive properties of two investigational devices compared to a test specimen reference.

18 - 70 years of age All Phase N/A
A Alexandra Edwards

Assessment of CymActive™ Catheter Technology for UrinAry ReTention and AcceptancE (The ACCTUATE Study)

The ACCTUATE study: Assessment of CymActive™ Catheter Technology for UrinAry reTention and acceptancE study will evaluate a novel catheter design that addresses the specific needs of male long term catheter users living in the community. The primary endpoint of the study will be tolerability, assessed by measuring patient-reported Quality of …

18 years of age Male Phase N/A
J Jordon D Bosse, PhD

Feasibility and Acceptability of Mindful Self-Compassion Among Transgender and Nonbinary Young Adults

The goal of this single-arm feasibility study is to evaluate the feasibility and acceptability of an 8-week mindful self-compassion intervention and associated data-collection plan among transgender and nonbinary young adults. Participants will be asked to: Complete weekly 2.5-hour virtual classes for 8 weeks and a 4-hour virtual retreat Practice specific …

18 - 25 years of age All Phase N/A
X Xiao Yang

A Study Comparing the Necessity of a Second Transurethral Resection in High-Risk Non-Muscle-Invasive Bladder Cancer Patients With Negative Results From Post-Initial Resection Urine Genome-Wide Low-Depth Sequencing

This study is a prospective, randomized, multicenter clinical trial aiming to enroll 428 patients with non-muscle-invasive bladder cancer (NMIBC) from the Department of Urology at Jiangsu Provincial People's Hospital and its affiliated centers, who have undergone their initial transurethral resection and are scheduled for a second resection. Within 1-6 weeks …

18 - 80 years of age All Phase N/A
A Amira Ali Heteba, Researcher

The Effect of XP-Endo Finisher Activation of Bioceramic Sealer on Postoperative Pain in Mandibular First Molar With Symptomatic Irreversible Pulpitis

The aim of endodontic obturation is to make a complete sealing along the length of the root canal system to ensuring the peri radicular tissue healing and sustained health. Disadvantages of gutta-percha-based root filling materials is lack of adhesiveness to canal wall dentin. So, a sealer or cement has to …

18 - 40 years of age All Phase N/A
R Roberto Berni Canani, MD

Hypoallergenicity of a Hydrolyzed Rice Protein-based Formula in Infants and Young Children With Cow's Milk Protein Allergy

The purpose of the study is to determine whether a new hydrolyzed rice protein-based formula is hypoallergenic in infants and young children with documented Immunoglobulin E (IgE)-mediated Cow Milk Protein Allergy (CMPA).

60 - 3 years of age All Phase N/A
C Cooper Neurological Institute

Chronic Subdural Hematoma Treatment With Intra-Arterial Bevacizumab Injection

The goal of this clinical trial is to test whether infusing bevacizumab into the middle meningeal arteries can be used to treat chronic subdural hematomas (cSDH). The main questions it aims to answer are: Is bevacizumab infusion safe in cSDH patients? Is bevacizumab infusion effective in treating cSDH?

18 years of age All Phase 1/2
W Weili Jia

HOPE From the Cerebellum: TMS-Induced Cognitive Recovery After Stroke

The objective of this clinical trial is to investigate the effectiveness and safety of repetitive transcranial magnetic stimulation (rTMS) in the cerebellum for individuals with post-stroke cognitive impairment. Participants will undergo rTMS in the cerebellar hemisphere opposite the lesion site, once daily for a total of five days.

18 years of age All Phase N/A

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