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Found 1,651 clinical trials

A Research Study to See if Two Different Formulations of Oral Semaglutide Are Equally Safe and Effective in Reducing the Blood Sugar Level in Japanese People With Type 2 Diabetes

The purpose of the study is to find out if the new tablet formulation oral semaglutide D is equally safe and effective as the approved oral semaglutide for treating Japanese people with type 2 diabetes. Participants will receive either oral semaglutide D (the treatment being tested) or oral semaglutide (the …

18 years of age All Phase 3

A Study of PATAS Trifluoroacetate Using Single Ascending Doses in Healthy Volunteers

The primary objective of this study is to evaluate safety and tolerability of single subcutaneous (SC) doses of PATAS in healthy subjects. The secondary objective of this study is to determine the pharmacokinetics (PK) of single SC doses of PATAS in healthy subjects.

18 - 55 years of age All Phase 1
J Jonas S Quist, PhD

A Feasibility Study of Optimal Non-Pharmacological Lifestyle Modifications in People With Type 2 Diabetes

The overall aim of this study is to examine the feasibility of a 12-month, two-arm lifestyle intervention to induce and maintain remission of type 2 diabetes (T2D). The findings from the feasibility study will inform the recruitment, design and delivery of the interventions in a 5-arm, 24-month randomised controlled trial.

18 - 75 years of age All Phase N/A

A Study of LY3549492 in Chinese Participants With Type 2 Diabetes Mellitus

The main purpose of this study is to investigate LY3549492 in Chinese participants with type 2 diabetes. Participation in the study will last about 18 weeks.

18 - 65 years of age All Phase 1
O Ortal Resnick, MD

A Low-Carb Approach to Treat Type 2 Diabetes in Pediatric Patients

The purpose of this project is to test the effect of a low carb diet compared to standard carb diet among adolescents with T2D over a 24-week period.

12 - 18 years of age All Phase N/A
M Matt Thomas, PhD

Time-restricted Eating for Patients With Type 2 Diabetes

This is a single-arm pragmatic clinical trial of time-restricted eating in patients with type 2 diabetes. Patients will be recruited from the University of Kentucky Barnstable Brown Diabetes Center. Subjects will participate in a 10-hour time-restricted eating intervention for 1-year.

18 years of age All Phase N/A
L Laura Van Den Mooter, Dr. (MD, PhD)

The Digital Diabetes Patient Reminder (DIPAR) Tool For Adults With Type 2 Diabetes

Digital health tools may present an opportunity to address these challenges by enhancing care delivery, improving patient engagement, and facilitating better disease management for chronic diseases such as type 2 diabetes mellitus (T2DM). This primary objective of this randomized controlled trial is to evaluate whether the Diabetes Digital Patient Reminder …

18 years of age All Phase N/A
K Kia E. Fonfara, Medical Doctor

Glucagon Resistance in Patients With MASLD and T2DM

The goal of this clinical trial is to investigate the sensitivity to glucagon in patients with type 2 diabetes mellitus (T2DM), with and without metabolic associated fatty liver disease (MASLD). The main questions it aims to answer are: Is the sensitivity to glucagon with respect to hepatic FA oxidation and …

30 - 70 years of age All Phase N/A
S Sania Srivastava

Using Continuous Glucose Monitoring to Quantify the Effects of NOURISH's Culturally Modified Meals on Asian Americans With Type 2 Diabetes

The investigators are hoping to determine whether tailoring the diet of someone with type 2 diabetes to their ethnic group while following American Diabetes Association guidelines can make a significant difference in their blood sugar controls. Participants will be required to wear a Continuous Glucose Monitor (CGM) for 1-month so …

18 years of age All Phase N/A
X Xiao K Tang

Quinoa Improves Glycolipid Metabolism and Glucose Fluctuation Based on β-Cell Function in Early-stage Type 2 Diabetes

The goal of this clinical trial is to explore whether quinoa diet can improve glycolipid metabolism and glucose fluctuations in patients with early-stage type 2 diabetes mellitus (T2DM) and observe its impact on islet β-cell function and insulin resistance in patients with early-stage T2DM (diagnosed according to the 1999 WHO …

20 - 70 years of age All Phase N/A

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