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Found 64,920 clinical trials
L Lee Kehoe, PhD

Dyadic Life Review Intervention for Older Patients With Advanced Cancer) and Their Caregivers

The purpose of this study is to test the feasibility of a pilot Randomized Controlled Trial (RCT) comparing Dyadic Life Review (DLR) intervention in older adults with advanced cancer and their caregivers to Care-as-Usual (CAU) group, which involves a referral to social work.

50 years of age All Phase N/A
A Alexandra Psihogios, Ph.D.

Mobile Health Intervention to Support Oral Chemotherapy Adherence in Adolescents and Young Adults With Leukemia

This is a small-scale micro-randomized clinical trial of a new mobile just-in-time adaptive intervention (JITAI) designed to promote oral chemotherapy adherence in adolescents and young adults (AYA) with acute lymphoblastic leukemia (ALL). The goals of this study are to determine intervention feasibility and acceptability.

14 years of age All Phase N/A
V Vikram Shenoy Handiru, PhD

Neuromodulation-Enhanced Use of RObotic BALANCE Training to Improve Balance Function in Individuals With Stroke

Our proposed study, "NEUROBALANCE Stroke,"; aims to evaluate the effectiveness of a combined intervention involving robotic balance training and noninvasive brain stimulation in improving balance function and postural control in individuals with chronic stroke. The study will recruit 45 participants who have had a stroke at least 6 months before …

18 - 75 years of age All Phase N/A
D Divya Adhia, Ph.D

Brain Network Stimulation for Chronic Low Back Pain.

This study looks at the non-invasive brain stimulation technique in people with chronic low back pain to see: How effective non-invasive brain stimulation is at improving pain intensity in people with chronic low back pain? How safe non-invasive brain stimulation is and what side effects there may be? What study …

18 - 75 years of age All Phase N/A
Q Qingyuan Zhang, Doctor

A Clinical Study of SYS6023 in Patients With Advanced Solid Tumors

This is an open-label, dose-escalation and cohort-expansion, multicenter Phase I study involving participants with advanced solid tumors.

18 years of age All Phase 1
A Anne-Marie Lake, MSc.

Managing Impact-related Leakage During Exercise Using Intravaginal Support

The goal of this study is to evaluate the effectiveness of using a regular menstrual tampon or a Uresta pessary to reduce urine leakage associated with running-induced stress urinary incontinence (RI-SUI) in females aged 18 and older. Secondly, the study aims to assess whether either intervention mitigates transient changes in …

18 years of age Female Phase N/A
D Dineth Karunamuni, MS

Thiamine Intervention and Coronary Artery Bypass Grafting

The purpose of this study is to gain a better understanding of the association between brain changes and cognitive deficits in coronary heart disease (CHD) patients undergoing coronary artery bypass grafting (CABG) and whether a low-cost thiamine intervention can be used to reduce post-CABG cognitive issues in CHD subjects.

60 - 80 years of age All Phase N/A
J Jenna Wong, MSc

Partial Neuromuscular Blockade in Acute Respiratory Distress Syndrome

PNEUMA is a preliminary safety and feasibility trial of a novel approach to the titration of neuromuscular blockade (NMB) to safe spontaneous breathing in patients with severe acute respiratory distress syndrome (ARDS) supported with veno-venous extracorporeal membrane oxygenation (VV-ECMO).

18 years of age All Phase N/A
A Andrea Russo

Delta Variation to Guide Hemodynamic Optimization

intraoperative hemodynamic optimization will be based on the percentage of variation of the parameters

18 years of age All Phase N/A
L Leyla Kaya, PhD

A Sustainable Choice to Reduce Carbon Footprint

This study aimed to evaluate the impact of carbon footprint education on breastfeeding practices among pregnant women.

18 - 35 years of age Female Phase N/A

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