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Found 64,920 clinical trials
R Ramara Chavez

Platelet Lysate vs Saline for Lumbosacral Radiculopathy

This is a randomized trial to evaluate and compare platelet lysate epidural injection to saline epidural injection for the treatment of lumbar radiculopathy (sciatica).

18 - 65 years of age All Phase N/A
F For more information at the NIH Clinical Center contact NCI/Surgery Branch Recruitment Center

Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies

Background Blood cancers (such as leukemias) can be hard to treat, especially if they have mutations in the TP53 or RAS genes. These mutations can cause the cancer cells to create substances called neoepitopes. Researchers want to test a method of treating blood cancers by altering a person s T …

18 - 120 years of age All Phase 1
T Tyler Lewis

CMV Immunity Monitoring in Lung Transplant Recipients

The purpose of this study is to determine the safety and feasibility of using a laboratory test to guide duration of antiviral prophylaxis with valganciclovir (medication used to prevent viral infections) after lung transplant. The laboratory test, inSIGHT™ CMV T Cell Immunity Panel, measures patients' immune response to a common …

18 - 99 years of age All Phase 2
R Rebecca Mollard, PhD

A High Protein Egg White Pudding for People With Kidney Failure (HiPE KF)

The goal of this clinical trial is to compare protein supplements in patients with kidney failure on dialysis. The main questions it aims to answer are: To determine whether the supplementation of egg white protein pudding in a population of individuals with kidney failure on dialysis is feasible. To determine …

18 years of age All Phase N/A
P Pei-Chi Wu, M.D.

Physical Therapy Intervention for Pelvic Organ Prolapses

Pelvic floor muscle training (PFMT) and pessaries are first-line non-surgical conservative treatments for pelvic organ prolapse (POP). High-Intensity Focused Electromagnetic Field (HIFEM) is a noninvasive and painless device, designed to promote muscle strengthening and growth and has become a popular treatment option for urinary incontinence in the field of gynecology. …

20 years of age Female Phase N/A
K Kıymet Yılmaz

Simulation Psychosocial Care Skills and Oncology Nursing

The aim of this study was to reveal the effect of simulation-based experience-based psychosocial care skills development programme on psychosocial care skills competence and professional quality of life of nurses working with oncology patients. The hypotheses of the study will be tested in accordance with the following guidelines. Hypothesis 1 …

years of age All Phase N/A
Q Qingyuan Zhang, Ph.D

TQB2930 Injection for the Treatment of HER2-positive Advanced Breast Cancer

TQB2930 is a HER2 bispecific antibody drug. This study aims to evaluate the efficacy and safety of TQB2930 combined with investigator's choice of chemotherapy versus trastuzumab combined with investigator's choice of chemotherapy in subjects with HER2-positive advanced breast cancer who have received at least two prior lines of anti-HER2 therapy …

18 - 75 years of age All Phase 3
R Reyhan A Doğan

The Effect of Progressive Relaxation Exercise

This clinical trial aims to evaluate the effect of a childbirth preparation program that includes progressive relaxation exercises on pregnant women's preferences for mode of delivery, their experience of labour pain, and breastfeeding comfort. Participants in the intervention group will receive a specially developed educational booklet and an audio CD …

18 - 49 years of age Female Phase N/A

Eltrombopag Induced Liver Dysfunction During Treatment of Immunethrombocytopenic Purpura

this study amis to assess the incidence and severity of liver dysfunction in ITP patients receiving eltrombopag.

18 - 75 years of age All Phase N/A

Sleep Restriction and Parental History of Hypertension

The purpose of this study is to research the effects of partial sleep deprivation (sleep restriction) in a group of individuals whose parents have high blood pressure compared to a group of individuals whose parents have normal blood pressure.

18 - 35 years of age All Phase N/A

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