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Found 64,920 clinical trials
S Shu-Bei Wang, MD

Perioperative Treatment of Combined Radiotherapy With SOX, Apatinib and Camrelizumab for Oesophagogastric Cancer

The study is being conducted to evaluate the efficacy, safety and tolerability of radiotherapy and chemotherapy, apatinib with camrelizumab in the neoadjuvant (prior to surgery) and adjuvant (after surgery) treatment of previously untreated adults with gastric and gastroesophageal junction (GEJ) adenocarcinoma.

18 - 75 years of age All Phase 2
M Mingwei Ma

68Ga-NY104 PET/CT Guided Radiation Therapy in CcRCC.

Radiation therapy (RT) is an effective treatment for patients with advanced-stage clear cell renal cell carcinoma (ccRCC). Current evidence has shown promising outcomes combining radiation therapy and standard systemic therapy in patients with metastatic/recurrent ccRCC. CAIX is a highly sensitive and specific biomarker expressed on ccRCC and in previous studies …

18 years of age All Phase 2
M Matthias Rostock, M.D.

Improvement of Quality of Life by Cannabinoids in Oncologic Patients

The goal is to explore whether the application of cannabis extract Avextra 10/10 solution is suitable to contribute to an improvement in the symptom burden and well-being of oncological palliative care patients. The primary objective of the study is to demonstrate the improvement in global symptom burden in the intervention …

25 years of age All Phase 2
D Dr. Mariam Salem, Professor

Impact of Balance Training in Community-Dwelling Older Adults After Recovery From COVID-19

This research investigates the impact of balance training on improving functional performance and reducing fall risk in community-dwelling older adults who have recovered from COVID-19. Post-COVID-19, many elderly individuals experience lingering physical impairments, including muscle weakness, decreased coordination, and balance deficits, which increase their vulnerability to falls. The study evaluates …

60 - 75 years of age All Phase N/A

Repetitive Transorbital Alternating Current Stimulation for Optic Neuropathies

The purpose of this study is to test the efficacy and feasibility of an intervention protocol for home-based repetitive transorbital alternating current stimulation (rtACS) for the treatment of visual impairment in people with optic neuropathy. The primary aims are to evaluate the effectiveness of home-based rtACS to ameliorate the progressive …

18 years of age All Phase N/A
M Morten Pallisgaard Støve, Msc.

Efficacy of a Home-based Stretching Program on Fibromyalgia Symptoms: a Randomised Controlled Trial

This randomised controlled trial will examine the clinical efficacy of a six-week, novel, home-based stretching programme compared to usual care on the effect of symptoms experienced by patients with fibromyalgia.

18 - 60 years of age All Phase N/A

To Test the Food for Special Medical Purpose in Perioperative Patients With Gastrointestinal Cancer

This is a prospective, randomized, open label, active-controlled, multi-centre, non-inferiority clinical trial. Aim of the study is to evaluate the efficacy and safety of Fresubin Support Drink in patients with gastrointestinal cancer undergoing surgical resection during the perioperative period.

18 - 75 years of age All Phase N/A
J Jianping Jia, MD,PhD

The Ketogenic Diet in the Treatment of Alzheimer's Disease

This research is a randomized, double-blind, placebo-parallel controlled, and multi-center clinical study in China, aiming to evaluate the tolerability, efficacy, and safety of JT821 (Ketogenic Diet) in the treatment of mild to moderate Alzheimer's disease. The ketogenic diet (KD) is a low-carbohydrate, adequate protein and high-fat diet. KD was shown …

50 - 85 years of age All Phase N/A

Effect of Walker vs Wheeled Device on Mobility After Total Knee Arthroplasty

Maneuverability is currently under appreciated by patients who are seeking mobility. This pilot study is examining how patients maneuverability and mobility will change with this novel mobility tool - A-Linker compared to the standard of care walker.

18 - 99 years of age All Phase N/A
D Daniel Xu

Switching of Sildenafil to Riociguat in CTEPH Patients

This study was designed to investigate the safety and efficacy of replacing phosphodiesterase 5 inhibitors (PDE5i) with riociguat in patients with Chronic thromboembolic pulmonary hypertension (CTEPH) who have undergone pulmonary angioplasty (BPA) and remains symptomatic despite treatments with PDE5i.

18 years of age All Phase 4

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