Found 64,783 clinical trials
Longitudinal Study to Investigate Different Transcranial Electrical Stimulation
This research investigates the effect of different frequencies of tACS (0 Hz, 30 Hz, 50 Hz, 70 Hz, 90 Hz) and tRNS with cognitive exercises in a regimen protocol of weeks, everyday. The study design is a longitudinal study design in which participants receive different tES randomly ordered. Treatments occur …
Omega-3 Supplementation for Pediatric Migraine
The purpose of the study is to assess the biochemical and clinical effects of omega-3 polyunsaturated fatty acid (PUFA) supplementation in youth suffering from migraine, including its effects on migraine disability, psychological distress, and overall quality of life. This study duration 12 weeks.
Neoadjuvant Adebrelimab in Resectable SCLC: A Randomized Trial
This study is a randomized, open-label, multicenter exploratory research aiming to evaluate the efficacy and safety of Adebrelimab in combination with chemotherapy (etoposide and platinum-based therapy) as neoadjuvant treatment for resectable stage I-IIIB (stage IIIB limited to T1-4N1-2M0) small cell lung cancer (SCLC). The study is primarily conducted at Tangdu …
Replicative Stress in Hair Follicle Stem Cells and Pathogeny of Hidradenitis Suppurativa
Hidradenitis Suppurativa is a recurrent chronic inflammatory follicular occlusive disease affecting hair follicles. HS is notoriously difficult and challenging to treat with a high morbidity impact and could be classified as an unmet medical need with no efficient therapeutic options. Objective Investigators previously showed that Outer Root Sheath Cells (ORS) …
Adding Calcitonin to Bupivacaine in Transversalis Fascia Plane Block for Cesarean Section
Evaluate calcitonin as an adjuvant to bupivacaine in ultrasound guided tansversalis fascia plane block
Fourth Ventricular Administration of Immune Checkpoint Inhibitor (Nivolumab) and Methotrexate or 5-Azacytidine for Recurrent Medulloblastoma, Ependymoma, and Other CNS Malignancies
The goal of this clinical trial is to assess the safety, toxicity, and antitumor activity of fourth ventricular infusions of nivolumab plus 5-azacytidine for recurrent ependymoma and nivolumab plus methotrexate for recurrent medulloblastoma and other CNS malignancies. Additionally, the study will explore immunologic responses to nivolumab. The hypothesis is that …
Effects of Protein Supplementation on Brain Function
Protein-rich foods may improve brain insulin-sensitivity, which is important for cognitive and metabolic health, and may also translate into an improved food intake regulation. It is therefore pertinent to delineate the effects of plant-derived proteins, which are a more sustainable alternative to animal-derived proteins, on brain insulin-sensitivity and related functional …
6-Month Trial of Chinese Herbal Treatments for Hair Loss and Gray Hair
This will be a 6-month randomized, double-blind, placebo-controlled trial. A total of 152 participants with hair loss, including some with gray hair, will be enrolled and randomly assigned to four groups. Each group will receive a combination of oral capsules and hair tonic, to be used as directed for 24 …
Non-Diet Nutrition Education and Its Effects on Eating Behavior, Body Image, and Well-Being in Adult Women
The goal of this clinical trial is to evaluate whether a non-diet nutrition education program can improve eating behaviors, body image, and well-being in normal-BMI women aged 19-35 years. The main questions it aims to answer are: Does participation in an 8-week non-diet nutrition education program improve eating behavior, body …
A Phase 2a Multicenter Clinical Trial of TB006 in Participants With Parkinson's Disease
The primary objectives of this study are to assess the efficacy of TB006 in improving motor function and to assess the safety of TB006 in participants with Parkinson's Disease (PD).
