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Found 64,783 clinical trials
S Suzanne Anjie, MD

Subcutaneous Interval Lengthening of Vedolizumab for Economic Research

Rationale: Subcutaneous vedolizumab is an effective maintenance therapy for patients with inflammatory bowel disease. Patients using subcutaneous vedolizumab (every 2 weeks) have higher vedolizumab serum trough concentrations than those who are treated with intravenous vedolizumab (every 4-8 weeks). Since biologic therapies such as vedolizumab are expensive, lengthening of the injection …

18 years of age All Phase 4
F Furqan Ahmed Siddiqi, PhD in Rehabilitation Sciences

Action Observation Training for Functional Performance in Children with Cerebral Palsy

This study is a randomized control trial and aims to determine the effects of Action Observation on balance and mobility in patients with cerebral palsy compared to training without action observation.

5 - 12 years of age All Phase N/A
S Sarguni Singh, MD

ALIGN for Older Adults With Cancer in SNFs

The goal of this clinical trial is to learn if it is possible to deliver a palliative care intervention called ALIGN (Assessing and Listening to Individual Goals and Needs) to hospitalized older adults with advanced cancer who are discharged to a skilled nursing facility and their caregivers. The main questions …

18 - 98 years of age All Phase N/A
Z Zhijie Wang, MD

Consolidation Radiotherapy vs. Observation in Oligoresidual Advanced Non-Small Cell Lung Cancer After Chemo-Immunotherapy

This clinical study investigates whether adding local radiation therapy (radiotherapy) to standard maintenance therapy benefits patients with advanced non-small cell lung cancer (NSCLC) who have a limited number of residual tumors after initial treatment. The primary objective is to determine if adding targeted radiation therapy to residual lesions prolongs progression-free …

18 years of age All Phase 2
M Ming-Ju Hsieh, MD, PhD

Different Re-training Durations in BLS Training Among Non-Professionals

Previous studies on compression-only CPR and AED training for the general public have primarily focused on the optimal retraining interval. However, the impact of different retraining durations remains unclear. This study explores how varying practice durations in Basic Life Support (BLS) training affect BLS performance among non-professionals.

18 years of age All Phase N/A
S Stefani Butts, MPH

The Test-to-PrEP Study

To compare the effectiveness of two social network strategies (direct distribution and referral-based distribution) in increasing HIV self-testing (HIVST) completion rates among social network contacts of current Pre-Exposure Prophylaxis (PrEP) clients.

18 years of age All Phase N/A
E Ester Sanchez, BSN

Calcium Carbonate to Augment Labor Contractions

The investigators think that calcium carbonate can act as an assistive medication to improve contractions during labor.

18 years of age Female Phase 4
A Anne-Elise C de Groen, MSc in Medicine

Ultralong-segment Barrett's Esophagus: Towards a Capsule-sponge Surveillance Strategy

The purpose of this study is to evaluate the Endosign capsule sponge test as a novel surveillance method in patients with an ultralong-segment Barrett's esophagus.

18 years of age All Phase N/A
K Kelly Caravella, PhD

Resources for Optimizing Outcomes in Toddlers on the Spectrum

The goal of this clinical trial is to assess whether telehealth-based Family Navigation (FN) expedites enrollment (e.g., reduces time in days) in community-based autism intervention for toddlers under the age of 4 living in Rural NC after their initial diagnosis of autism. The main questions it aims to answer are: …

1 - 99 years of age All Phase N/A

Study of Bictegravir/Emtricitabine/Tenofovir Alafenamide in Newborns Exposed to HIV

The goal of this clinical study is to learn more about the study drug, Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF), safety, tolerability, and pharmacokinetics (how B/F/TAF is absorbed, modified, distributed, and removed from the body of the participants) in neonates exposed to human immunodeficiency virus type 1 (HIV-1). The primary objective of this …

- 120 years of age All Phase 1

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