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Found 64,783 clinical trials
M Muhammad Asif Javed, MS

SWOC Activities on Balance, Gait and Endurance in Children With Autism Spectrum Disorder

Autism Spectrum Disorder (ASD) is a developmental disorder characterized by challenges in social communication, social interaction, repetitive behaviors, and restrictive interests. Affecting 0.2-2% of children, ASD often includes motor growth retardation, which worsens over time. The disorder is more commonly diagnosed in boys, and its cause is believed to be …

8 - 12 years of age All Phase N/A

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

The purpose of this study is to characterize the safety and tolerability of ALTA3263 in adults with advanced solid tumors with KRAS mutations.

18 years of age All Phase 1

Topical Ruxolitinib Cream for Refractory Cutaneous Dermatomyositis

This study will assess the safety and efficacy of topical ruxolitinib for treating the refractory cutaneous manifestations in patients with dermatomyositis. The investigators' hypothesis is that topical ruxolitinib will be both safe and effective for such patients.

18 - 89 years of age All Phase 2
S Shaimaa N AboElazm, Dean

Effect of Feldenkrais Method on Balance in Patients With Mechanical Low Back Pain

The goal of this clinical trial is to learn if Feldenkrais method affects balance in patients with mechanical low back pain. The main questions it aims to answer is: does Feldenkrais method affects balance in patients with mechanical low back pain. Participants will: Be assessed for inclusion using slump and …

18 - 45 years of age All Phase N/A
S Serkan kumbasar, Assistant Professor

Post-Hysterectomy Vaginal Length: Horizontal vs. Vertical Closure

This prospective clinical study aims to evaluate the impact of vaginal cuff closure orientation-horizontal versus vertical-on postoperative total vaginal length in patients undergoing vaginal hysterectomy combined with lateral suspension. By comparing anatomical outcomes between the two closure techniques, the study seeks to determine which method better preserves vaginal length, potentially …

35 - 65 years of age Female Phase N/A
T Tariq A Lalmahomed, MD

Two-Fraction Ultrahypofractionated Radiotherapy With Focal Boost for Intermediate Risk, Localized Prostate Cancer

The goal of this clinical trial is to assess the non-inferiority irradiating low and intermediate risk, localized prostate cancer in two fractions of radiotherapy, compared to five fractions of radiotherapy which is the standard of care. The main question it aims to answer are: Do participants in the interventional arm …

18 years of age Male Phase N/A
M Mei Dong Zhou, Doctor

A Study of LUCAR-G79 in Subjects With Relapsed/Refractory Autoimmune Diseases

This is a prospective, single-arm, open-label and dose-escalation Investigator Initialed study to evaluate LUCAR-G79 in adult subjects with relapsed/refractory autoimmune diseases.

18 - 70 years of age All Phase 1
A Administrator

Herbal Evaluation Of Artemisia Annua For Small Intestinal Bacterial Overgrowth

Small intestinal bacterial overgrowth (SIBO) can cause symptoms like bloating, stomach pain, and changes in bowel movements, significantly affecting quality of life. Many people with irritable bowel syndrome (IBS) also have SIBO, and there is growing recognition of how important it is to address this condition. Artemisia annua has shown …

18 years of age All Phase 1/2
S Sevil Günaydın, PhD.

Effects of Hot Sacral Massage and Shower Application With Partner Support on Labor

This study was designed to determine the effect of warm sacral massage with cherry pits and showering with partner support on perceived labor pain, birth experience, and birth comfort. A total of 150 pregnant women, 50 in each group, were planned to be included in the study. Volunteers who agreed …

18 years of age Female Phase N/A

Study of Lenacapavir as a Once-Yearly Injection for HIV Pre-exposure Prophylaxis (PrEP)

The goal of this clinical study is to learn more about the study drug lenacapavir (LEN), safety, tolerability, and pharmacokinetics (how LEN is absorbed, modified, distributed, and removed from the body of the participants) of once-yearly intramuscular for HIV pre-exposure prophylaxis (PrEP) in people with an indication for PrEP. The …

16 years of age All Phase 3

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