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Found 64,783 clinical trials
A Aitor Azkàrate Martínez, Dr

A Study of Roginolisib (IOA-244) in Combination With Dostarlimab With or Without Docetaxel in Metastatic Non Small-cell Lung Cancer (NSCLC) Patients

The goal of this clinical trial is to learn how roginolisib works in combination with dostarlimab with or without docetaxel in adult patients with advanced non small-cell lung cancer. The main questions it aims to answer are: To compare across the treatment arms the proportion of patients with a reduction …

18 years of age All Phase 1/2
A Alessia Martina Trenta, Dr

The Effects of Body Scan on Enteroception in Patients With Heart Failure

The study aims to explore the effects of body scan on enteroception in people with heart failure

18 - 75 years of age All Phase N/A
A Allen C Sherman, PhD

Solifenacin Compared to Clonidine for Reducing Hot Flashes Among Breast Cancer Patients

Hot flashes present a considerable problem for many breast cancer patients; these symptoms may be intensified by hormonal therapies, such as aromatase inhibitors or tamoxifen. This study examines the value of solifenacin (a muscarinic acetylcholine receptor antagonist) in reducing hot flashes, compared with clonidine (a medication often used for treating …

18 years of age Female Phase 2
A Abhishek Jaywant, PhD

Mobile Cognitive Behavioral Therapy for Stroke

This study aims to assess the feasibility and acceptability of "MAYA", a mobile cognitive behavioral therapy app for anxiety and mood disorders, in adults who have had a stroke.

40 - 79 years of age All Phase N/A

A Study of Safety and Efficiency of AND017 in Patients With β-thalassemia

This is a phase II, randomized, double-blinded, placebo-controlled study to treat patients with transfusion-dependent and non-transfusion dependent β -thalassemia with AND017 and optimal supportive care, including blood transfusion and iron removal, based on the clinician's judgment and practice.

18 - 65 years of age All Phase 2
玲玲 余

Manual Acupuncture (MA) for Asymptomatic Hyperuricemia (HUA)

Assess the effectiveness of manual acupuncture in modulating serum uric acid levels among patients diagnosed with asymptomatic hyperuricemia.

18 years of age All Phase N/A

320-detector Computed Tomography to Assess Myocardial Extracellular Volume Fraction in Patients With Atrial Fibrillation Before AF Ablation.

This study explores the relationship between myocardial fibrosis and patient outcomes in Atrial Fibrillation (AF), specifically after catheter ablation. It aims to use Cardiac CT, an accessible tool, to measure left ventricular extracellular volume (ECV) as an indicator of fibrosis. The study will assess if higher ECV levels correlate with …

21 years of age All Phase N/A
L Leah Morse

A Study of Barzolvolimab in Patients With Atopic Dermatitis

The purpose of this study is to assess the efficacy and safety of barzolvolimab in adults with Atopic Dermatitis

18 years of age All Phase 2
H H WM van Laarhoven, MD, PhD, PhD

The Effect of exeRcise And Diet on Quality of Life in Patients With Incurable Cancer of Esophagus and Stomach (RADICES)

The survival of patients with incurable gastroesophageal cancer can extend over a year with anticancer therapy. However, the number of patients with deteriorating quality of life in this patient group steadily decreases over time during the treatment. Potentially reversible causes related to deterioration of quality of life are diminished muscle …

18 years of age All Phase N/A
B Bintou Njai, MBBS

A Confirmatory Trial of Adjunctive NAC to Prevent Post Tuberculosis Lung Disease

The goal of this clinical trial is to evaluate if N-acetylcysteine (NAC) works to prevent post-tuberculosis lung disease (PTLD) in patients with severe pulmonary impairment. It also aims to assess the safety of NAC. The main questions the study aims to answer are: Does NAC improve lung function (FEV1%) over …

18 - 65 years of age All Phase N/A

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