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Found 65,447 clinical trials
S Sarah Samperi

A Randomised Controlled Trial, Of N-Acetyl Cysteine (NAC), for Premanifest Huntingtin Gene Expansion Carriers

NAC-preHD is a phase II randomized placebo controlled study of oral NAC among premanifest HD gene expansion carriers, with clinical and radiological outcome at three years.

18 years of age All Phase 2
Y Yea-Ru Yang, PhD

Biofeedback Gait Training on Gait Quality in Stroke

Post-stroke gait dysfunction is characterized by reduced gait velocity and stride length, along with gait asymmetry and instability. Gait asymmetry and instability are considered as indicators for gait quality, which affect independence and quality of life in individual with stroke. Previous studies have suggested that gait biofeedback is a promising …

20 - 80 years of age All Phase N/A
Y Yueyang Zhong

Clinical Evaluation of Extended Depth-of-focus Intraocular Lens in Refractive Cataract Surgery: a Randomized Controlled Trial

The goal of this clinical trial is to compare the clinical outcomes of two extended depth-of-focus intraocular lens after cataract surgery. The randomized controlled trail will enroll 90 participants. The participants will be randomly assigned to implant Tecnis Synergy ZFR00 or Tecnis Symfony ZXR00 intraocular lens. Follow-up visit will be …

40 - 80 years of age All Phase N/A

A Phase III Study of YL201 in Relapsed Small Cell Lung Cancer

This study was designed to compare the efficacy and safety of YL201 with Topotecan Hydrochloride in subjects with relapsed small cell lung cancer (SCLC).

18 - 75 years of age All Phase 3
X Xiaorong HOU, PhD

Hypofractionated Online Adaptive Radiotherapy of Breast Cancer

The goal of this clinical trial is to explore the application of online adaptive radiotherapy in patients who receive moderate hypofractionated or ultrafractionated radiotherapy after breast cancer surgery. The main questions it aims to answer are: Can online adaptive radiotherapy improve the accuracy of dose delivery? In patients undergoing online …

35 - 70 years of age Female Phase 2
S Samira Taeb, MSc

Positron Emission Mammography and Liquid Biopsy in Women With High-risk Breast Screenings

The goal of this research study is to evaluate the performance of two experimental tests, namely Liquid Biopsy and Positron Emission Mammography (PEM) in women at high risk of breast cancer. The plan for this study is to assess whether findings from the combination or each individual test can assist …

18 years of age Female Phase N/A
A Arline Allera

Osteopathic Manipulative Treatment RCT and Computational Modeling for Head Injuries in Mixed Martial Artists

The purpose is to test how osteopathic medicine (OMM) improves recovery after a hit to the head during Mixed Martials Arts (MMA). The small changes in the bone, joints, and fluids during head injuries may lead to traumatic brain injury (TBI). The OMM is adjusting the body with the doctors' …

18 - 50 years of age All Phase N/A
B Ban A Majeed, PhD

BREATHE Free: a Pilot Feasibility Trial

The overall purpose of this pilot study is to assess the feasibility and acceptability of an in-person faith-based intervention to help people stop tobacco use. The study will address use of different types of tobacco products, such as smoking combustible cigarettes, cigarillos and little filtered cigars, and using/vaping electronic nicotine …

18 years of age All Phase N/A
P Patricia Martinez-Merinero, PhD

Treatment of Lateral Epicondylalgia With Shock Waves

Lateral epicondylalgia (LET) is characterized by pain, decreased muscle strength of the wrist extensor muscles, and disability. Among the treatments proposed in the literature, both focal shockwave therapy and radial shockwave therapy have been considered effective in the management of this musculoskeletal disorder. The objective of this study is to …

18 - 70 years of age All Phase N/A
Y Yunfei Chen, MD

A Clinical Study on the Efficacy and Safety of Herombopag in the Treatment of Senile Primary ITP

The objective of this study was to evaluate the efficacy and safety of Herombopag in the treatment of elderly patients with ITP.

60 years of age All Phase 2

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