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Found 64,783 clinical trials
M Marie-Pierre REVEL, PhD

Involvement of General Practitioners in Lung Cancer Screening

The main objective is to evaluate the adherence of smoking patients to lung cancer screening by low-dose CT scan, when proposed by the general practitioner.

50 - 74 years of age All Phase N/A
L Liankun Ren, MD

The Safety and Efficacy Evaluation of Everolimus as an Adjunctive Treatment for Focal Refractory Epilepsy

The aim of this study is to evaluate the clinical efficacy of everolimus as an adjunctive therapy for refractory epilepsy. The significance lies in addressing whether the mTOR inhibitor sirolimus has antiepileptic adjunctive effects for a broader range of patients with refractory epilepsy, with the hope of providing a new …

18 - 60 years of age All Phase N/A
H Hira Amjad, BDS

Effectiveness of Cryotherapy on Endodontic Pain

This is a randomized , prospective , control trial to assess the effectiveness of intracanal cryotherapy on post operative pain after root canal treatment in patients with symptomatic apical periodontitis

20 - 40 years of age All Phase 2
J Jinhong Chen, M.D

Cadonilimab Combined With Regorafenib as A Third-line Treatment in Patients With MSS CRLM

This study is a single-arm, open-label, multicenter clinical study to evaluate the efficacy and safety of Candonilimab (AK104) combined with Regorafenib for the treatment of MSS colorectal liver metastasis. Candonilimab (AK104) is a humanized IgG1 bispecific antibody that targets PD-1 and CTLA-4.

18 - 75 years of age All Phase 2
T Thibaut CASSOU-MOUNAT

Prostate Cancer Burden and Heterogeneity Evaluation Towards Liquid Biopsy: a Correlation Study to 18FDCFPyL PET and Patients Outcome

This is a prospective, monocentric, proof of concept study aims to identify in prostate cancer patients, a potential relationship between CTC-PSMA positivity and 18F-PET-PSMA results as well as patient outcome. Patients with 18F-PET-PSMA indication will perform imaging extension work-up as part of current practice. If they agree to participate in …

18 years of age Male Phase N/A

Liom Non-invasive Continuous Glucose Monitor "Clinical Demo" (niCGM)

This is a single-centre, multiple cohort, open study.

18 - 65 years of age All Phase N/A
S Secrétariat Promotion NA

Visual (Path)Ways in Multiple Sclerosis - Part II

Multiple sclerosis (MS) is an inflammatory demyelinating and degenerative disease of the central nervous system. The mechanisms of neuro-axonal loss remain incompletely elucidated. An acute demyelinating lesion will produce both immediate and delayed axonal loss. Immediate axonal loss is linked to the occurrence of axonal transection. Delayed axonal loss is …

18 years of age All Phase N/A

A Clinical Study of B007 in the Treatment of Generalized Myasthenia Gravis.

The purpose of this study is to evaluate the efficacy and safety of B007 in subjects with generalized myasthenia gravis.

18 - 70 years of age All Phase 2/3
B BEDRİYE AK, Associate Prof.Dr.

The Effect Of Model-Based Dıgıtal Game On Metabolıc Control, Self-Effıcıency And Qualıty Of Lıfe In Chıldren Wıth Type 1 Dıabetes

This study was planned to determine the effect of model-based digital game on metabolic control, self-efficacy and quality of life in children with T1DM.

8 - 13 years of age All Phase N/A
L Louis HOFFART, MD

Evaluation of the Effects of Virtual Reality on Preoperative Anxiety in Refractive Surgery

The objective of this study is to determine to what extent the use of a software application prior to refractive surgery involving multisensory immersion (visual and auditory) in a hypnotic and relaxing sound and visual environment can reduce anxiety levels. The assessment of preoperative anxiety levels will be based on …

18 years of age All Phase N/A

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