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Found 65,447 clinical trials
U Ulrike Dapunt, Prof. Dr. med

Fall Risk Assessment and an Exercise Intervention for Prevention of Falls in Multiple Myeloma Patients

Approximatly one third of the population over the age of 65 fall at least once a year. The risk of falling is in increased in older patients with tumor diseases. In addition to high treatment and care costs for the healthcare system, falls often lead to a decrease of quality …

18 years of age All Phase N/A
H Hala S Abdel-Ghaffar, MD

Effect of Magnesium Sulphate Pretreatment in Pediatric Abdominal Surgery

In this study, the investigators will compare the effect of magnesium sulphate pretreatment on the onset and duration of intense and deep neuromuscular Block of rocuronium versus Cis-Atracurium and on the period of no response to nerve stimulation in children undergoing elective open abdominal surgeries.

2 - 12 years of age All Phase 2/3

Rivaroxaban for Children Aged Over 2 Years With Giant Coronary Artery Aneurysms After Kawasaki Disease

Based on population pharmacokinetic model-based simulation, a 15 mg-equivalent, age-, and bodyweight-adjusted dosing regimen for Chinese children with giant coronary artery aneurysms after acute Kawasaki disease was proposed. This exploratory trial aims to evaluate the feasibility, safety and effectiveness of rivaroxaban compared to warfarin for thromboprophylaxis in children aged over …

2 - 18 years of age All Phase 4

Combined Effects of Plyometric and Endurance Training Among Female Hockey Players

Athletes need plyometric training as well as endurance training to enhance their speed, strength and agility in the field. Plyometric exercise involves stretching the muscle immediately before making a rapid concentric contraction. The combined action is commonly called a stretch-shortening cycle (SSC). Similar gains of maximal strength have been reported …

18 - 24 years of age Female Phase N/A
E Emily W. Lopes, MD

Personalized Risk Estimation for Crohn's Disease (PRE-Crohn's): Implementation and Feasibility

The aim of this study is to develop and assess the feasibility and effect of a web-based, personalized risk-estimation for Crohn's disease (PRE-Crohn's) tool on behaviors and biomarkers associated with risk for Crohn's disease in unaffected first-degree relatives of patients with inflammatory bowel disease. We hypothesize that personalized risk disclosure …

14 years of age All Phase N/A
J Jessica Shim, MD

Glycemic Regulation as Endometriosis Adjunct Treatment

The goal of this pilot trial is to learn if a novel non-hormonal treatment, metformin hydrochloride, works to treat pelvic pain in young women with endometriosis. The main questions it aims to answer are: Is metformin superior to placebo in alleviating pain symptoms in young women with endometriosis? Does metformin …

15 - 35 years of age Female Phase 2
M Moko Cheung, Bsc

A Pilot Study of Synbiotics in Adults With Depressive Symptoms

This study aims to explore the efficacy and safety of a synbiotic formula (MQU10) in improving mood and well-being in adults with mild to moderate depressive symptoms.

18 years of age All Phase N/A
J Jan Derks, PhD

Use of a Bone Substitute Material in the Surgical Therapy of Furcation Defects

The aim of this randomized clinical trial is to evaluate the potential benefit of the use of a bone substitute material in the treatment of furcation degree II-involved molars. The main question it aims to answer is: What is the benefit of the adjunctive use of a bone substitute material …

18 years of age All Phase N/A
W Wiam Belkaid, PhD

Impact of PEG Bowel Preparation on Gut Microbiome Composition Recovery

The main objective is to evaluate the impact of intestinal preparation on the composition, diversity and metabolome of the intestinal microbiota.

18 - 70 years of age All Phase 1
F Fei Li, Doctor

Efficacy of Nutritional Supplements on Children With Autism Spectrum Disorder

The goal of this clinical trial is to learn if nutritional supplements could alleviate the clinical symptoms in children with autism spectrum disorder. It will also learn about the safety of these nutritional supplements. Researchers will compare the combination of nutritional supplements and behavioral intervention, to behavioral intervention alone, to …

30 - 72 years of age All Phase 2

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