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Found 65,447 clinical trials
J Joseph LaBossiere, MD FRCSC

Antibiotic Prophylaxis for Neurogenic Bladder Botox

Injection of Botox into the bladder is a procedure used to treat neurogenic overactive bladder at the Dianne and Irving Kipnes Urology Centre in the Kaye Edmonton Clinic. A common complication following bladder Botox is bladder infection. There are no well-studied preventative antibiotics given at the time of bladder Botox …

18 - 100 years of age All Phase 2
G Gretchen Roman, PT, DPT, PhD

Health Protection and Promotion of Sign Language Interpreters Through Implementation of Total Worker Health®

Using mixed-methods and a clinical efficacy trial design, the overall objective of this study will employ implementation strategies to adapt and evaluate a previous integrated Total Worker Health® (TWH®) program and pilot test its efficacy on sign language interpreter well-being. The central hypothesis is that interpreters in the health protection …

18 years of age All Phase N/A
Z Zhiyu Chen, PhD

Vitamin E Combined With Fruquintinib and Tislelizumab in Microsatellite Stabilized Metastatic Colorectal Cancer Patients

The goal of this clinical trial is to learn about efficacy of Vitamin E in combination with Fuquinitinib and Tirelizumab in patients with microsatellite stabilized mCRC who have failed standard therapy. The main question is to explore the survival time, safety and tolerability of the treatment. At the same time, …

18 years of age All Phase 2

Adebrelimab + Apatinib in SCLC Maintenance Therapy

This prospective clinical study aims to evaluate and observe the efficacy and safety of Atezolizumab combined with Apatinib in maintenance therapy for extensive-stage small cell lung cancer using a single-arm trial design. The study is planned to be conducted in Shaanxi Province, China, with an initial target enrollment of 60 …

18 - 75 years of age All Phase 2
S Sidra Faisal, MS.CPPT

Combined Effects of Blow Bottle Device and Postural Drainage in Moderate to Severe Elderly COPD Patients

It will be a randomized clinical trial. Age of selected subjects will be between 40 to 70 years. Data will be collected from Wazirabad institute of cardiology. There will be 2 groups i.e. group A will receive combination of blow bottle technique and postural drainage and group B will receive …

40 - 60 years of age All Phase N/A
J Jenny Duerinckx

Anovo Surgical System in Ventral Hernia

The study is aimed to clinically assess the AnovoTM Surgical System in ventral hernia procedures. Extensive preclinical testing of the system's integrity and safety has been performed to assure adequate safety for this trial.

18 years of age All Phase N/A
Y Yongxian Hu, PhD

Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of r/r B-NHL Clinical Research

A Study of Metabolically Armed CD19 CAR-T Cells Therapy for Patients With Relapsed and/or Refractory B-cell Non-Hodgkin lymphoma

19 - 70 years of age All Phase N/A

Effect of Hypoxia on FMISO PET to Response to Lu-177 PSMA Treatment

It is aimed to evaluate hypoxia before Lu-177 PSMA treatment in prostate cancer and to show its effect on treatment success with 18F-FMISO PET imaging, which allows in-vivo evaluation and quantification of tumor hypoxia, which is known to be one of the factors affecting radiotherapy resistance.

18 years of age Male Phase N/A

Pharmacokinetics of Drospirenone Only Pills: A Pre- and Post-Bariatric Surgery Study

The purpose of this study is to investigate whether bariatric surgery affects Drospirenone only pills absorption

18 - 45 years of age Female Phase 1/2
C Cynthia J Santana, BA

Starting Technology in At Risk Type 1 Diabetes Study

Diabetes technology has revolutionized T1D management, disparities in technology access are evident among racial-ethnic minorities, patients with lower socioeconomic status and those with poorly controlled T1D (A1c>8.5%). In order to examine whether diabetes technology can reduce diabetes care burdens and enhance outcomes among some of highest need patients, diabetes technology …

18 years of age All Phase N/A

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