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Found 64,783 clinical trials

Targeted Plasticity Therapy for PTSD

Objectives of this study are to provide continued safety assessment for the ReStore system, and to gain further estimates of the effect size of Vagus Nerve Stimulation (VNS) therapy with Prolonged Exposure Therapy (PE) compared to PE with placebo (sham) stimulation in participants with posttraumatic stress disorder (PTSD)

22 - 79 years of age All Phase N/A

Study of SIM0508 Alone and in Combination in Patients With Advanced Solid Tumors

This is a multicenter, open-label, first-in-human study to evaluate the safety,efficacy, and PK/PD characteristics of SIM0508 as a single agent and in combination with olaparib in participants with locally advanced/metastatic solid tumors.

18 years of age All Phase 1
A Aslaug Karlsdóttir

The MAGiC™ Cardiac Ablation European Study

The purpose of the first phase of this feasibility study is to gather safety and performance data on MAGiC to support European marketing approval.

18 years of age All Phase N/A

L-carnitine Supplementation in Rheumatoid Arthritis Patients

This study aims to evaluate the effect of l-carnitine as add- on therapy for improving the outcome in rheumatoid arthritis patients.

18 - 60 years of age All Phase 2
G Gökhan AÇMAZ, Prof.Dr.

The Effect of Stress Ball Used During Intra Uterine Insemination on Pain, Anxiety, Comfort and Physiological Parameters

This study aimed to determine the effects of holding the patient's hand and using a stress ball during the Intrauterine Insemination procedure on pain, anxiety, comfort, and physiological parameters. This study will be conducted as a randomized controlled trial with a pre-test-post-test procedure in the IVF Unit of a Medical …

18 - 50 years of age Female Phase N/A
J Juhaina Salim Al Maqbali, MSc

The Use of Melatonin for Delirium Prevention in Medically Hospitalized Patients

The high prevalence of delirium in hospitalized older adults, with significant associated morbidity and mortality, emphasize the need for effective prevention strategies. Limited trials have explored melatonin's potential in preventing delirium among patients admitted to general medical wards. Previous trials on melatonin's preventive role in medical wards had limitations, necessitating …

65 years of age All Phase 2/3
M MERVE BASARDI

Effectiveness of Dynamic Neuromuscular Stabilization Breathing Exercises With Schroth in Adolescent Idiopathic Scoliosis

In our study, the degree of scoliosis curvature in volunteers will be determined using full-body standing X-rays. Additionally, the rotation degree of the spinal curvature in volunteers will be assessed with a scoliosis meter (a type of ruler) through the forward bending test while standing. To measure the impact of …

10 - 18 years of age All Phase N/A

Blood Flow Restriction for Optimizing Balance in Parkinson's Disease

This study is being done to understand how reducing blood flow (BRT) during balance-challenging strengthening exercises (instability resistance training, or IRT) can help improve symptoms of Parkinson's disease.

40 - 85 years of age All Phase N/A

Efficacy of Dexmedetomidine-Propofol Versus Ketamine-Propofol for Sedation

This study aims to compare efficacy of sedation between Dexmedetomidine-Propofol and Ketamine-Propofol combinations in the upper or lower gastrointestinal system endoscopy. We compare between 2 combinations as regard hemodynamic stability, post operative side effects as occurrence of delirium, nausea, vomiting, headache, hallucination or agitation.

18 - 60 years of age All Phase N/A
T Taha M Agmy

Stellate Ganglion Block Versus Oral Medication in Treatment of Palmar Hyperhidrosis

The aim of the study is to compare between ganglion block versus combined oral anticholinergic and antidepressant drugs on treatment of palmar hyperhidrosis

20 - 45 years of age All Phase N/A

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