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Found 65,447 clinical trials
C Connie J Rogers

Probiotics and Gut Health

This study evaluates the effects of probiotic consumption on inflammatory outcomes and measures of gut health. Participants will be given yogurt with probiotics for one period and yogurt without probiotics for another, with a break in between. These periods will occur in random order.

55 - 75 years of age All Phase 1/2
M Marlene A. Rodríguez Barragán, MD, MSc

Effect of Three Training Programs on the Cardiovascular Condition of Individuals with Spinal Cord Injury

Objective: Describe the effect of different aerobic training programs on the autonomic nervous system (ANS), cardiovascular condition, body composition, metabolic profile, movement and functional independence in patients with spinal cord injury (SCI). Design: Randomized clinical trial Participants: Individuals in the chronic phase of SCI. Interventions: Three training programs: continuous aerobic …

18 years of age All Phase N/A
S Sofia Marini, PhD

Blue-green Space Physical Activity: the "Parco Del Mare" Study

This study protocol, describe the innovative study intervention which will be performed in a green-blue space in Italy in order to investigate on the improvements in wellbeing following participation in the study. This will be significant because it will provide evidence on the effectiveness of the supervised physical activities carried …

18 years of age All Phase N/A
T TingBo Liang, MD, PHD

Camrelizumab Plus Apatinib in Combination With GEMOX (Gemcitabine and Oxaliplatin ) in Patients With Locally Advanced Biliary Tract Cancer

This is a phase II open-label, one-arm, multicenter study aimed to explore the efficacy and safety of perioperative (neoadjuvant and adjuvant) treatment for patients with advanced biliary tract carcinoma.

18 - 75 years of age All Phase 2
L Luigi Fontana, MD

The Effect of Cord Blood Serum Eyes Drops Administer in Patients With Severe Keratopathy Related to EGFR-I Treatment

The study aim to evaluate the efficacy of cord blood eye drops in the healing of the damaged corneal epithelium.

18 years of age All Phase N/A

Galunisertib Combined With Capecitabine in Advanced CRC With PM

This is a two-center open-label non-randomized proof of principle study consisting of a dose-finding part (phase I) and phase II study with Simon two-stage design investigating the anti-tumor activity of the combination of capecitabine and galunisertib in patients with colorectal cancer with peritoneal metastases.

18 years of age All Phase 1/2
D Deanna Teoh, MD

Intraperitoneal FT536 in Recurrent Ovarian, Fallopian Tube, and Primary Peritoneal Cancer

This is a single center Phase I clinical trial of FT536 administered intraperitoneally (IP) 3 times a week for one week for the treatment of recurrent gynecologic cancers. A short course of outpatient lymphodepleting chemotherapy is given prior to the first dose of FT536 to promote adoptive transfer.

18 years of age All Phase 1
R Rebecca E Kotcher, MD

Blue Light as an Anti-inflammatory and Analgesic Strategy in Thoracic Trauma

The main goal of this clinical trial is to learn if light therapy improves pain and inflammation in adults with painful rib fractures. The main question it aims to answer is: Does bright blue light therapy in addition to standard pain treatments improve pain with breathing in adults with painful …

18 years of age All Phase N/A
D David Gomez-Almaguer, MD

Low Dose Teclistamab in Newly Diagnosed Multiple Myeloma Patients

This single-arm, open-label study aims to determine the efficacy and safety of low-dose, limited-duration teclistamab as a consolidation scheme in newly diagnosed multiple myeloma (NDMM) patients.

18 years of age All Phase 2
F Francesco Ceci

Exploring the Tumor Micro-Environment with 68Ga-FAPi-46 PET/CT in Breast Cancer

This study is a prospective, non-interventional, open-label study to evaluate the glucose metabolism and the expression of the imaging agent 68 Gallium-Fibroblast Activation Protein Inhibitor-46 (68Ga-FAPi-46) with PET imaging, in woman affected by Breast Cancer (BC) and referred to diagnostic imaging work-up prior to primary therapy.

18 years of age Female Phase N/A

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