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Found 64,783 clinical trials
S Stephen Huddle

To Validate Point Mini User Needs

The objective of the device feasibility study will be to validate the user needs of the Point Mini system. This study will be a single group intervention model where one group of 5 children with partial-hand upper limb loss will be asked to perform several tasks. Successful completion of a …

5 - 15 years of age All Phase N/A
Y Ying Cheng, Bachelor

PM8002 in Combination With Paclitaxel Compared With Chemotherapy as Second-line Treatment in Small Cell Lung Cancer

PM8002 is a bispecific antibody targeting PD-L1 and VEGF. This study will evaluate the efficacy and safety of PM8002 in combination with Paclitaxel as second-line treatment for SCLC

18 - 75 years of age All Phase 3

Nimotuzumab Combined With TGP as First-line Therapy in Patients With Recurrent/Metastatic Nasopharyngeal Carcinoma

The goal of this study is to learn the efficacy and safety of nimotuzumab combined with toripalimab and gemcitabine/cisplatin regimen treatment recurrent/distant-metastasis nasopharyngeal carcinoma.

18 - 75 years of age All Phase 2
H Hyungsuk Kim, M.D. Ph.D.

Effect of Atelocollagen Injection in Patients With Calcific Tendinitis

Assess the clinical outcomes using atelocollagen injection in patients with calcific tendinitis.

20 - 69 years of age All Phase 4
S Satvir S Dhillon

Skeletal Muscle Function in Interstitial Lung Disease

Dyspnea (i.e. breathlessness) and exercise intolerance are common symptoms for patients with interstitial lung disease (ILD), yet it is not known why. It has been suggested that muscle dysfunction may contribute to dyspnea and exercise intolerance in ILD. Our study aims to: i) examine differences in the structure and function …

40 - 80 years of age All Phase N/A
M Marta Cenac-Mehedinti

A Research Study Exploring How Musculoskeletal Function and the Autonomic Nervous System Relate to Visceral Pain in Women With and Without Dysmenorrhea (Painful Periods).

The purpose of this clinical trial is to determine if women with dysmenorrhea demonstrate an increased musculoskeletal and autonomic nervous system response to a painful visceral stimulus compared to controls. A secondary aim is to determine if interoceptive awareness moderates this relationship. The designed methodology aims to elucidate the intricate …

18 - 35 years of age Female Phase N/A
S Senior Clinical Psychologist (PSS1)

A Pilot Study on Animal-Assisted Intervention in Correctional Settings

Mental health concerns such as depression, anxiety, and post-traumatic stress are particularly prevalent among incarcerated individuals and are considered risk factors for recidivism. Leveraging the natural human-animal bond, animal-assisted intervention (AAI) offers a less threatening alternative to engage incarcerated individuals and address their mental health needs. As an initial effort …

18 years of age All Phase N/A
H Hilde S Ludvigsen, Master

eBehandling - Health and Work for Patients in Specialist Mental Health Care

Mental health problems and disorders affect one in every five amongst the working- age adults in the countries of the Organization for Economic Cooperation and Development. This constitutes a major public health challenge that also has large implications for work participation and productivity. Major depression and anxiety are the most …

18 - 65 years of age All Phase N/A
D Department of Clinical Physiology and Nuclear Medicine

The New Combined PET-MR System NextGen PET-MR With Syngo MR XA80A: Evaluation of Diagnostic Image Quality and Usability (Software and Hardware) in the Clinical Setting.

This clinical investigation is used to evaluate the novel PET-MR scanner and it is a clinical investigation under MDR. The focus is on the evaluation of the diagnostic image quality in a clinical setting, considering the speed of the examination and the new functionalities to minimize the patient's lying times. …

18 years of age All Phase N/A
K Kim Madden, PhD

Kinematic and Mechanical Alignment Randomized Trial

Knee replacement surgery is the second most common surgery in Canada. People who have very painful knee arthritis usually receive a knee replacement where the surgeon aims to make everyone's knee as straight as possible (called mechanical alignment). Mechanical alignment focuses on making the implant last as long as possible. …

18 years of age All Phase 4

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