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Found 64,920 clinical trials
R Rami Darwich, MD, PhD

Efficacy of Selective Laser Trabeculoplasty Targeting Nasal Versus Inferior 180-degree

The purpose of this study to optimize Selective Laser Trabeculoplasty (SLT) application when used in the management of open angle glaucoma (OAG)

18 years of age All Phase N/A
C Changju Qu

Chidamide Combined With Brentuximab Vedotin Regimen for CD30+ PTCL Patients

To evaluate the efficacy and safety of chidamide combined with brentuximab vedotin regimen for CD30 positive PTCL patients who are unfit for chemotherapy.

18 - 75 years of age All Phase N/A
L Lorenzo Rossi, MD

Intratumoral INT230-6 Followed by Neoadjuvant Immuno-chemotherapy in Patients With Early TNBC. INVINCIBLE-4-SAKK

About 10-20% of all individuals with breast cancer have a so-called triple-negative tumor (TNBC). This type of breast cancer has a particularly unfavorable course and a higher mortality rate compared to other forms of breast cancer. Research studies show that it is important for individuals with TNBC to achieve a …

18 years of age All Phase 2
C Chunling Wang

Oxygen Study-Orelabrutinib Combined With Obinutuzumab(O2) for First-Line Treatment of Marginal Zone Lymphoma

This is a multi-center, prospective study. The main purpose is to evaluate the efficacy and safety of Orelabrutinib combined with Obinutuzumab for previously untreated MZL.

18 years of age All Phase 2
Y YiWen Chien, PhD

Effects of UC-II, Glucosamine and Curcumin Supplementation on Knee Pain and Inflammation.

This research evaluated the effects of UCII, glucosamine and curcumin supplementation on knee pain and inflammation.

20 - 70 years of age All Phase N/A

A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy

This will be a prospective, open-label, single-arm, multi-center, pilot study to evaluate the safety, tolerability, and preliminary efficacy of low-intensity focused ultrasound (LIFU) neuromodulation using NaviFUS System in patients with drug-resistant unilateral or bilateral temporal lobe epilepsy (DR-TLE).

18 years of age All Phase 1/2
L Laura Reid Marks, PhD

The Increasing Mindfulness Engagement Project

The goal of this clinical trial is to examine the feasibility and acceptability of different types of text messages and a integrated gaming app to increase engagement in a mindfulness mobile health application. Does receiving text messages increase engagement in a mindfulness app? Does an integrated gaming app increase engagement …

18 - 29 years of age Male Phase N/A

A Study Comparing Personalized Radiation Therapy With Standard Radiation Therapy in People With HPV-Positive Throat Cancer

The researchers are doing this study to find out if a personalized approach to chemoradiation therapy (which may include a lower dose of radiation) is as effective as the standard chemoradiation therapy in people with HPV-positive throat cancer. Other purposes of this study include looking at the following: Whether a …

18 years of age All Phase 3
J Jessica Strolin (Goltzman)

PRESERVE & CONNECT: Impact Study of the BPC

The PRESERVE & CONNECT project is a multi-site randomized control trial of the Breakthrough Parenting Curriculum: Navigating Trauma Across Generations (BPC) in rural and racially and ethnically diverse communities in Vermont and Connecticut.

years of age All Phase N/A
J John O. Prior, MD, PhD

[68Ga]Ga-FAPI-46 in Staging of Head and Neck Carcinomas

The trial focuses on assessing the role of [68Ga]Ga-FAPI-46 in head and neck squamous cell carcinomas (HNSCC) staging before surgery. In the context of metastasis, cancer-associated fibroblasts (CAFs) emerge as pivotal contributors to the creation of a microenvironment conducive to future metastases. CAFs exert their influence through intricate mechanisms, including …

18 years of age All Phase 2

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