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Found 65,447 clinical trials
C Crystal Wong

Assessment of the Initial Efficacy and Safety of BRM424 Ophthalmic Solutions in Patients With Neurotrophic Keratitis

The objective of this study is to obtain initial efficacy of BRM424 in patients with Stage 2 and Stage 3 NK and evaluate safety and tolerability.

18 years of age All Phase 2
R Rulin Zhuang, MD,PhD

Cancer of Esophagogastric Junction: Optimized Sweet Versus Ivor-Lewis

This study is being done to see whether Optimized Sweet Procedure is superior than the Ivor-Lewis Procedure Esophagectomy with better long-term outcome and acceptable postoperative short-term outcome or not.

18 - 80 years of age All Phase N/A

A Study on the Efficacy and Safety of Multi-mode Ablation Combined With Systemic Therapy in the Treatment of CRCLM

The goal of this study is to evaluate the efficacy and safety of multi-mode ablation combined with systemic therapy including PD-1(programmed death receptor 1) inhibitor for colorectal cancer liver metastasis and furthermore to clarify its application value by comparing preoperative and postoperative immune indicators.

18 - 75 years of age All Phase 2
U Uta Ouali, M.D.

Interventions for Clinical High Risk Youth in Tunisia

Study participants will take part in one of the two types of treatments aimed at improving daily functioning as follows: either a Cognitive Training (CT) Program or an Enhanced - Treatment as Usual (E-TAU) Group. All group treatments will be provided at Razi Hospital and one of the sessions will …

14 - 28 years of age All Phase N/A
f faculity of dentistry Cairo university

Evaluation of The Stability of Orthodontic Treatment After First Premolar Extraction Using Combined Retention Protocol

The aim of this study is to compare between the stability of anterior and posterior segments in both arches using bonded lingual retainers versus a combined protocol of retention (bonded lingual retainer and vacuum formed retainers). The effect of different treatment changes achieved on the post-treatment stability will be studied …

18 years of age All Phase N/A
E Erlei Zhang

Palliative Hepatectomy Combined With Targeted Therapy and Immunotherapy for Advanced Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors and the leading cause of cancer-related death worldwide. Surgical resection has always been the best hope for long-term survival of patients with HCC. However, due to the fact that most patients are already in the middle and late stages …

18 - 75 years of age All Phase 1
B BULENT YASAR, PROF

Patients With Irritable Bowel Syndrome and Physiotherapy

The research will be planned on 72 individuals between the ages of 18-65 who were diagnosed with irritable bowel syndrome at Istanbul Medipol University Çamlıca SUAM Gastroenterology Polyclinic. Patients will be divided into 3 groups; High-intensity interval training and a disease-specific nutrition program for the first group, and a disease-specific …

18 - 65 years of age All Phase N/A
K Karen Devon, MD, MSc, FRCSC, FACS

Parathyroid Allotransplant for Severe Refractory Hypoparathyroidism

Hypoparathyroidism following thyroid surgery presents significant challenges, often leading to debilitating symptoms and reduced quality of life despite conventional treatment. Having now reported the first successful case of a deceased donor fresh tissue parathyroid allotransplant with immunosuppression in a transplant-naive recipient, the purpose of this study is to further assess …

19 years of age All Phase N/A

Xengenic Cortical Membranes Versus Connective Tissue Graft With Coronally Advanced Flap for the Treatment of Peri-implant Soft Tissue Dehiscences: A Randomized, Controlled Clinical Trial

Peri-implant soft tissue dehiscences represent a common complication in implant dentistry, often leading to esthetic and functional challenges. Current treatment options, including Xengenic cortical membranes and connective tissue graft with coronally advanced flap, aim to promote soft tissue regeneration and improve clinical outcomes. However, there is a need for comparative …

20 - 50 years of age All Phase 2
A Amna Shaid, t-DPT

Effects of Sprint Interval Training on Field Hockey Players.

Field hockey is a team sport that is played using sticks and balls. Player's motions are impromptu and determine how competitive matches are played. Athletes can enhance their performance through a variety of training regimens. "Sprint Interval Training," for short bursts of maximal or supramaximal exercise, is one type of …

18 - 30 years of age All Phase N/A

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