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Found 64,783 clinical trials
W Weijing Zhang

A Study of MHB048C in Patients With Advanced Solid Tumors

This is a first-in-human, open-label, multicenter Phase I/II study of MHB048C in patients with advanced solid tumors. The study was designed to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of MHB048C monotherapy.

18 years of age All Phase 1/2
C Cristiana Griffoni, PhD

Active Informed Consent: a New Solution to Improve and Objectively Test the Patient Understanding of Complex Surgical Procedures Proposals

This is an interventional, non-pharmacological, randomized controlled superiority study (RCT), multicenter, open label, parallel group. The aim is to evaluate the effectiveness of a new preoperative information method, based on multimedia tools and on the objective control of understanding by the patient candidate for spinal or urological surgery.

18 years of age All Phase N/A
C Christine DeLorenzo, PhD

The Role of mGluR5 in CBT-I

This is mechanistic clinical trial that evaluates the role of one of the glutamate receptors (mGluR5) in cognitive behavioral therapy for insomnia (CBT-I) as a common pathway in improving sleep and depression.

18 years of age All Phase 4
F Florence Larkin, B.S.

Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric)

The proposed study will evaluate a new approach to cognitive rehabilitation of mTBI using a brain stimulation technique called "Remotely Supervised Transcranial Direct Current Stimulation combined with Cognitive Training" (RS-tDCS+) which has shown promise for improving complex attention in both healthy and clinical populations. RS-tDCS+ is a home-based, low-risk, non-invasive …

18 - 60 years of age All Phase N/A
W Wang Jianxiang

uCD7 CART for Relapsed or Refractory CD7 Positive Hematologic Malignancies

The aim of this study was to evaluate the safety and efficacy of universal CD7 CART (uCD7 CART) cells in the treatment of patients with relapsed/refractory CD7-positive hematologic malignancies. In this single-arm, open-label, single-center, Phase 1 clinical trial, two cohorts were set up: (1) relapsed and refractory acute myeloid leukemia …

18 - 70 years of age All Phase 1
H Heng Mei, M.D., Ph.D

CD7-specific CAR-T Cell in the Treatment of CD7-positive Relapsed/Refractory Hematologic Tumors

This study is a single-center, open, prospective single-arm clinical study of patients with CD7 postive relapsed / refractoryhematological tumors to evaluate the safety and efficacy of CD7-specific CAR-T cells in relapsed / refractory hematological tumors while collecting pharmacokinetics and pharmacodynamics indicators of CAR-T cells.

3 - 75 years of age All Phase 1/2
M Mimi Mun Yee Tse, PhD.

Effectiveness of GO for Transitional Housing Residents

The goal of this pre-post study is to enhance the health and wellness of the residents in the Concordia Tsat Sing Kong Transitional Housing Estate. This study aims to evaluate the effectiveness of the Green Oasis (GO) wellness program in: Increase health awareness and engaging in health promoting activities, including …

10 years of age All Phase N/A
M Mohammadreza Pourahmadi, Ph.D., Postdoc Research Fellow

Effectiveness of Dry Needling in Patients With Chronic Nonspecific Low Back Pain

Low back pain is a major health problem that affects psychosocial, economical, functional and physical aspects of the patients' life. The aim of this study will be to investigate the effectiveness of dry needling on pain, functional disability, postural control and pain pressure threshold in patients with chronic nonspecific low …

18 - 45 years of age All Phase N/A
A Abdelrahman M Salah, MD

Desarda's Technique Versus Lichtenstein's Technique Hernia Repair in Management of Elective Non-Complicated Inguinal Hernia

This study aims to compare Desarda's technique and Lichtenstein's technique of hernia repair in managing elective, non-complicated inguinal hernia.

14 years of age All Phase N/A
T Talia Williams, BA

Making Healthy Habits Stick

The aim of this project is to help increase physical activity maintenance in cancer survivors.

19 years of age Female Phase N/A

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