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Found 65,447 clinical trials
J Jan Martínek, prof,MD,PhD

ENDOPLY System in Humans: a Pilot Study

Prospective, non-randomized study aimed at defining the initial pattern of gastric plication with the ENDOPLY System, and assess feasibility, ergonomics and safety of the device Prospective, single-centre, open label, consecutive enrolment

18 - 60 years of age All Phase N/A
D Diego Serrano Muñoz, PhD

tdCS Combined With Treadmill Training in Patients With Multiple Sclerosis

This clinical trial aims to evaluate the therapeutic effectiveness of transcranial direct current stimulation (tDCS), a non-invasive technique that modulates cortical excitability, in combination with gait training in patients with multiple sclerosis (MS). The study focuses on improving balance and walking ability, which are commonly impaired in this population. A …

18 years of age All Phase N/A

The Effect of Daratumumab in Patients with Monoclonal Gammopathy of Renal Significance (MGRS) in Finland

The goal of this clinical trial is to learn if drug daratumumab works to treat kidney diseases other than AL-amyloidosis that fall under the category of monoclonal gammopathy of renal significance (MGRS). The main questions it aims to answer are: Does daratumumab have an effect on the patients' renal function …

18 years of age All Phase 2
H Haibo Jia

RESTORE Imaging: an OCT-IVUS Imaging Substudy of RESTORE Trial

The objective of this imaging substudy of RESTORE trial is to demonstrate the superiority of drug-coated balloon (DCB) treatment on non-flow limited vulnerable plaque as compared to guideline-directed medical therapy (GDMT) in improving plaque stabilization in patients with acute coronary syndrome.

18 - 80 years of age All Phase N/A
E Eva Asselmann, Prof. Dr.

Prevention of Mental Disorders Through Self-efficacy Interventions

Low self-efficacy is a transdiagnostic risk factor for several mental disorders. Self-efficacy refers to one's belief that one is capable of performing a behavior necessary to successfully complete a task or achieve a goal. Consistent with theoretical models and empirical findings, individuals with low self-efficacy are more likely to perceive …

18 - 30 years of age All Phase N/A
M Megan Lattanze

Evaluating Microarray Pharmacogenetic Testing in Cancer Patients

The purpose of this research is to evaluate the impact of a microarray PGx test on prescribing/dosing of drugs and cancer treatments in patients with cancer who are currently eligible for single-gene DPYD testing.

18 years of age All Phase N/A
R Robert DiSilvestro, Ph.D.

Curcumin & Astaxanthin for Lowering Triglyceride Readings and Inflammation

Two dietary supplements are each being compared to a placebo for the ability to help maintain triglycerides in the normal range. The subjects will be adult men and women with moderately high TG values. Serum triglycerides will be measured before and after 6 weeks of taking 1 capsule per day …

21 - 59 years of age All Phase N/A
S Saeed Sarwar, MBBS

Outcomes of a Single Chest Drain vs Two Drains

Esophagectomy is a major surgical procedure done for carcinoma of esophagus. Usually bilateral chest tubes are placed in surgery for prevention of fluid accumulation in chest. However such procedure limits patients mobility and increases severity of pain. recent studies suggest that a single drain can be safe and effective. our …

years of age All Phase N/A

A Multi-centered,Randomized,Double-blind,Placebo-controlled Study to Evaluate the Efficacy and Safety of SHR-1703 in Eosinophilic Asthma

The purpose of this study is to evaluate the Pharmacodynamic, Efficacy and Safety of SHR-1703 in Asthma Patients with Eosinophil Phenotype

12 years of age All Phase 3

Study of BHV-1300 in Graves' Disease

The purpose of this study is to determine if BHV-1300 is a safe treatment in participants with Graves' Disease and to explore its effect on disease-specific biomarkers.

18 - 65 years of age All Phase 1

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