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Found 65,447 clinical trials

Feasibility Study of Deep Learning-based MDixon Quant for Quantitative Assessment of Chemotherapy-induced Fatty Liver

The purpose of this study is to quantitatively assess the changes in liver fat content in cancer patients before and after treatment. The main questions it aims to answer are:How does the liver fat fraction change before and after chemotherapy? In this study, patients undergoing mDixon Quant scanning are subjected …

18 - 80 years of age All Phase N/A
W Wiebren Tjalma, MD, PhD

Developing a Combined Molecular Screening and Triage Test for Cervical Cancer in Self-samples

The goal of the COMBISCREEN project is to develop a fully molecular cervical screening and triage approach that is applicable on self-samples, which are an easily accessible and non-invasive source of biomarkers. The project allows a one-step screening and triage modality and thereby identifies women with clinically relevant disease that …

25 - 64 years of age Female Phase N/A
D Dr Tahir Saghir

Use of Export in Primary Percutaneous Coronary Intervention

Aim of this single center randomized open label trial with blinded in-hospital outcomes assessment is designed with aim to compare manual thrombus aspiration followed by percutaneous coronary intervention (PCI) strategy with PCI alone.

18 years of age All Phase N/A
M Medhat M Kamal

Assessment of Treatment Efficacy Using Smile Arc Marginal Ridge Approach Versus MBT Chart Method for Bracket Positioning

The goal of this randomized clinical trial is to evaluate the effect of Smile Arc Marginal Ridge Approach (SAMRA) versus MBT chart method for bracket positioning on orthodontic treatment results. The main questions it aims to answer are: Is there a difference in orthodontic treatment results between smile arc marginal …

11 - 30 years of age All Phase N/A

Clinical Trial Evaluating the Safety and Efficacy of Nucleus Pulposus Allograft in Participants With Degenerative Disc Disease

VIA Disc NP is a non-surgical intervention intended to supplement nucleus pulposus tissue in degenerated intervertebral discs. This is a randomized, sham-controlled, multi-center, double-blind clinical trial with an open label roll-in period of one participant per site in which participants with lumbar discogenic pain associated with DDD will receive one …

22 - 85 years of age All Phase N/A
J Jin Jie

Clinical Trial of WBC100 Capsule in Relapsed/Refractory Acute Myeloid Leukemia

The goal of this clinical trial is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of WBC100 capsules in patients with relapsed or refractory acute myeloid leukemia (R/R AML). The main questions it aims to answer are: What is the safety and tolerability profile of WBC100 in R/R …

18 years of age All Phase 1
H Helen SAVARIEAU, MSc

Evaluation of the Efficiency of the PRPP (Perceive, Recall, Plan and Perform) Task Analysis System on Support and Orientation Decisions for People With Aging Psychiatric Disorders (PATPV) Living in Independent Housing.

Over the past 30 years, mental health policy has been geared towards increasing the number of people receiving care in the community, with a reduction of over 50% in the number of general psychiatric beds. The WHO recommends the implementation of alternatives to hospitalization, through the development of outpatient and …

40 - 65 years of age All Phase N/A
H Haris Ali, MD

Ruxolitinib With Tacrolimus and Methotrexate for the Prevention of Graft Versus Host Disease in Pediatric and Young Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome

This phase II trial tests how well ruxolitinib with tacrolimus and methotrexate work to prevent the development of graft versus host disease in pediatric and young adult patients undergoing allogeneic hematopoietic cell transplant for acute myeloid leukemia, acute lymphoblastic leukemia, or myelodysplastic syndrome. Ruxolitinib is a type of medication called …

2 - 22 years of age All Phase 2
A Adnan Arshad, DPT

Comparing Mirror Therapy and CIMT for Hand and Arm Function in Post-Stroke Patients

The goal of this clinical trial is to find out whether Mirror Therapy (MT) combined with Constraint-Induced Movement Therapy (CIMT) improves hand and arm function after a stroke. The study will also compare this combination to CIMT alone. The main questions it aims to answer are: Does combining MT with …

40 years of age All Phase N/A
H Hojin Lee, MD, PhD

Intrathecal Morphine Injection Versus Continuous Wound Infiltration After Pancreaticoduodenectomy

This is a prospective randomized open-label noninferiority trial that compares intrathecal morphine injection and continuous wound infiltration after open pancreaticoduodenectomy.

19 years of age All Phase N/A

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