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Found 65,447 clinical trials
B Bonaventure Yiu Ming IP, MB ChB

Intravenous Thrombolytic Therapy in Acute Ischemic Stroke Patients on DOAC

Direct oral anticoagulants (DOAC) have emerged as safe and efficacious ischemic stroke prophylaxis for non-valvular atrial fibrillation (NVAF). All four DOACs - apixaban, dabigatran, edoxaban, rivaroxaban - were associated with lower risks of major bleeding compared to warfarin. Listed as core essential medicines by the World Health Organization, DOAC prescriptions …

18 years of age All Phase N/A
A Ashley D Kendall, PhD

Feasibility Testing a Meditation App for Professionals Working With Youth in the Legal System

This feasibility clinical trial aims to assess the feasibility of implementing a 1-month app-based meditation program with officers in the juvenile legal system and other professionals working directly with legal-involved youth.

18 years of age All Phase N/A

A Study of LCAR-AIO CAR-T Cells for Treating Relapsed/Refractory Neurological Autoimmune Diseases

This is a prospective, single-arm, open-label, dose-exploration and expansion clinical study of LCAR-AIO in adult subjects with relapsed/refractory neurological autoimmune diseases.

18 - 70 years of age All Phase 1
S Sara Khan, MD

ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

This is a Phase II open-label study to investigate the safety and efficacy of ACT001 in patients with DIPG and H3K27-altered HGG.

12 - 39 years of age All Phase 2
C Caroline Makowski

Adapting the FACETS Program to Sickle Cell Disease

Adaptation of a fatigue management program combining the principles of cognitive-behavioral therapy and energy conservation strategies (FACETS program) for a population of adult patients with sickle cell disease (Drépa-FACETS program).

18 years of age All Phase N/A
M Moroni Berrios

A Study to Evaluate a Postbiotic in Supporting Weight Loss and Metabolic Health

This study aims to evaluate the impact of a specific oral postbiotic supplement on metabolic health in overweight adults.

18 - 65 years of age All Phase N/A
P Peiguo Wang, doctor

Lparomlimab and Tuvonralimab Injection in Combination With TACE and Lenvatinib in the Treatment of Second-Line Therapy for Unresectable Intermediate-to-Advanced Hepatocellular Carcinoma

Major objectives To evaluate the efficacy of lparomlimab and Tuvonralimab injection (QL1706, an Anti-PD-1/ CTLA-4 Combined Antibody) in combination with TACE and lenvatinib as second-line therapy in patients with unresectable intermediate-to-advanced hepatocellular carcinoma.

18 years of age All Phase 2
Y Yin Fong Leung, MBBS

Comparison Between Propess and Cook Double-balloon Catheter for Cervical Priming

The investigators aimed to compare efficacy and safety of Propess versus Cooks double-balloon catheter for cervical ripening with an unfavorable cervix in term pregnancy.

18 - 50 years of age Female Phase 4
Ü Ülkü yılmaz, PHD

The Effect of Foot Care Training Given to Diabetic Hemodialysis Patients on Foot Care Behavior

Diabetic foot causes hospitalization, amputation and serious health problems in individuals. This situation also leads to loss of productivity of the individual, negatively. diabetic foot can be reduced by 85% with good foot care, education and a multidisciplinary team approach. Diabetes is observed in the majority of hemodialysis patients. Foot …

18 years of age All Phase N/A
C Clinical Trial Referral Office

Methotrexate, Erlotinib, and Celecoxib for the Treatment of Recurrent/Metastatic Oral Cavity Cancer in a Rural Midwest United States Population

This phase II trial gathers information on the feasibility, safety, and effect of giving methotrexate, erlotinib, and celecoxib in treating oral cavity cancer that has come back after a period of improvement (recurrent) or that has spread from where it first started (primary site) to other places in the body …

18 years of age All Phase 2

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