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Found 65,447 clinical trials

To Test the Food for Special Medical Purpose in Perioperative Patients With Gastrointestinal Cancer

This is a prospective, randomized, open label, active-controlled, multi-centre, non-inferiority clinical trial. Aim of the study is to evaluate the efficacy and safety of Fresubin Support Drink in patients with gastrointestinal cancer undergoing surgical resection during the perioperative period.

18 - 75 years of age All Phase N/A
J Jianping Jia, MD,PhD

The Ketogenic Diet in the Treatment of Alzheimer's Disease

This research is a randomized, double-blind, placebo-parallel controlled, and multi-center clinical study in China, aiming to evaluate the tolerability, efficacy, and safety of JT821 (Ketogenic Diet) in the treatment of mild to moderate Alzheimer's disease. The ketogenic diet (KD) is a low-carbohydrate, adequate protein and high-fat diet. KD was shown …

50 - 85 years of age All Phase N/A

Effect of Walker vs Wheeled Device on Mobility After Total Knee Arthroplasty

Maneuverability is currently under appreciated by patients who are seeking mobility. This pilot study is examining how patients maneuverability and mobility will change with this novel mobility tool - A-Linker compared to the standard of care walker.

18 - 99 years of age All Phase N/A
D Daniel Xu

Switching of Sildenafil to Riociguat in CTEPH Patients

This study was designed to investigate the safety and efficacy of replacing phosphodiesterase 5 inhibitors (PDE5i) with riociguat in patients with Chronic thromboembolic pulmonary hypertension (CTEPH) who have undergone pulmonary angioplasty (BPA) and remains symptomatic despite treatments with PDE5i.

18 years of age All Phase 4
S Samvel Bardakhchyan, MD, PhD

Assessment of the Safety and Efficacy of Balstilimab in Combination With Botensilimab for the Treatment of Non-Small Cell Lung Cancer (IMMONC0008)

The goal of this study is to see if the combination of immunotherapy agents botensilimab and balstilimab is safe and effective in participants with metastatic non-small cell lung cancer (NSCLC) as a first-line treatment.

18 years of age All Phase 2
J Jobeth Lim Kar Yee

A Smart Digital Workflow Towards High Precision and Through-Put Production for Removable Partial Dentures

Tooth loss is a major chronic problem in dentistry and edentulous elderly endures poorer quality of life worldwide. Removable partial dentures (RPDs) are the most widely accepted and cost-effective treatment for patients to restore oral functions. RPDs contain three components including the metal framework, denture base and acrylic teeth. Conventionally, …

21 years of age All Phase N/A
L Landon L CHAN, MBChB, MSc

SBRT With Immunotherapy and Atezo-Bev in HCC With Major Portal Vein Thrombosis

Patients with PVTT involvement is a significant healthcare burden as they are present in up to 40% of patients with HCC at diagnosis. These patients exhibit a poorer prognosis compared to patients without PVTT, as a result they were often excluded from existing pivotal clinical trials [9-11]. Without management, the …

18 years of age All Phase 2
C Chad Stecher, PhD

StandUPTV Habits: Feasibility Trial for Maintaining Reductions in Sedentary Screen Time

Our goal in this study is to further refine StandUPTV, an application designed to reduce SST in adults in our first study (ASU IRB # STUDY00012109), for the StandUPTV Habits program. This program aims to establish a non-sedentary habit triggered by an alert from the StandUPTV application after participants engage …

23 - 64 years of age All Phase N/A
D DongTao Meng

A Clinical Trial of LBL-024 Combination Drug in Patients With Advanced Solid Tumours[Substudy 01(NSCLC)]

An open-label, multicenter, phase II clinical study to evaluate the efficacy and safety of LBL-024 in combination with other drugs for the treatment of patients with advanced solid tumour.

18 - 75 years of age All Phase 2
M Mikael Sonesson, Assoc. Prof.

Comparing a Novel Closed Exposure Technique to a Conventional Method for Palatally Impacted Maxillary Canines

A multi-center Randomized Clinical Trial, (RCT) on treatment effectiveness of two different closed surgical exposure techniques, one including additional bone removal and a second conventional without removal of additional bone, during treatment of palatally impacted maxillary canines. A comparison between the two methods regarding the anchorage situation for the incisors …

10 - 18 years of age All Phase N/A

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