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Found 64,783 clinical trials
O Ozhan Ozdemir, Professor

Anxiety, Physiological Parameters, Patient Satisfaction and VR in Gynecological Oncology Surgery

Surgical procedures often cause significant anxiety in patients, particularly among women undergoing gynecological oncology surgeries. Preoperative anxiety is a common and preventable condition that can negatively affect both physiological parameters and the overall surgical experience. It may lead to increased heart rate, elevated blood pressure, respiratory distress, and psychological discomfort, …

18 years of age Female Phase N/A
B Berkeley Limketkai, MD, PhD

Impact of Prebiotics in Ulcerative Colitis

The cause of inflammatory bowel disease (IBD) is currently unknown, although partly attributed to interactions among genetic risk polymorphisms, environmental factors, gut microbiome, and host immunity. Diet, particularly those with plant-based products, have been shown in prior research to improve gut microbial composition, which has been linked to different IBD-related …

18 - 85 years of age All Phase N/A
Q Qurat ul Ain Saeed, MS-OMPT

ADDITIONAL EFFECTS OF MOBILIZATION WITH MOVEMENT WITH UPPER QUADRANT CORE STRENGTHENING IN ROTATOR CUFF RELATED PAIN:A RANDOMIZED CONTROLLED TRAIL

This study is a randomised control trial and the purpose of this study is to determine the additional effects of mobilization with movement with upper quadrant core strengthening in rotator cuff related pain .

18 - 65 years of age All Phase N/A
M Małgorzata M Wójcik, Dr

Use of TDCS Stimulation in Neurological and Gynaecological Conditions

The aim of the study is to test the effect of tDCS stimulation on upper and lower limb function in neurological patients and to reduce pain in gynaecological patients. And the impact of tDCS stimulation on patients' quality of life. Standardised questionnaires will be used for pre- and post-stimulation evaluation.

18 - 90 years of age All Phase N/A
S Sabina Rizzi, Medical Doctor

Simulation-Based Training for Epidural Analgesia Placement

Epidural analgesia is the gold standard for labor pain management, widely recommended by the WHO and included in Italy's essential levels of care (LEA) since 2017. Despite its clinical benefits and high maternal satisfaction, the procedure remains technically challenging, particularly for anesthesia residents. In our institution, around 40% of laboring …

18 years of age All Phase N/A
R Rabia CAGLAYAN, RN

Impact of Education Methods on HPV Knowledge and Screening Behavior

The aim of this study is to evaluate the effect of two different health education methods (one based on motivational interviewing) on women's HPV knowledge, cervical cancer health beliefs, and screening behaviors in women aged 30-65. A total of 96 healthy women who are registered at the Incirli Family Health …

30 - 65 years of age Female Phase N/A

Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy.

The purpose of this study is to determine if zigakibart is safe and effective for long-term use in patients with immunoglobulin A nephropathy (IgAN). This is an extension study for patients who have already completed an another zigakibart study.

18 - 100 years of age All Phase 3
L Lynn F Buchwalder, M.S.

Albumin Assisted Diuresis in Patients with Cirrhosis and Ascites

A small, pilot proof-of-concept placebo-controlled trial to explore the effects of albumin on diuresis in patients with cirrhosis, ascites and lower extremity edema. We will additionally investigate albumin's effect on preventing neurohumoral activation, and acute kidney injury after diuresis.

18 years of age All Phase 2
N Nitin Ohri, MD

Thoracic Radiotherapy and Inhibition of PD-1 and LAG-3 for Locally Advanced Non-Small Cell Lung Cancer

Determine anti-tumor efficacy by characterizing response rates on positron emission tomography (PET) following three cycles of induction immunotherapy with cemiplimab and fianlimab without chemotherapy for locally advanced non-small cell lung cancer (LA-NSCLC).

18 years of age All Phase 2

A Study to Investigate Safety and Pharmacokinetics of Intravenous Cefiderocol/Xeruborbactam in Participants With Renal Impairment

A Phase 1, Open-label, Single-dose Study to Determine the Safety and Pharmacokinetics of Intravenous Cefiderocol/Xeruborbactam (S-649228) in Participants with Renal Impairment

18 - 80 years of age All Phase 1

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