Found 65,447 clinical trials
A Phase 2 Study of PTX 100 in Patients With Relapsed/Refractory CTCL
This is an open-label, phase 2 randomized study to evaluate the efficacy, safety, pharmacokinetics (PK) and pharmadynamics (PD), of PTX-100 monotherapy at 500 or 1000 mg/m2 in patients with relapsed/refractory Cutaneous T-Cell Lymphoma (CTCL). PTX-100 will be administered by IV infusion over 60 minutes on days 1 to 5 of …
Post Isometric Relaxation Versus Post Facilitation Stretch Techniques in Chronic Low Back Pain
This randomized controlled trial will be conducted at Riphah Rehabilitation Clinic and Spinacure clinic in Lahore over a 9-month period. A sample size of 42 participants, aged 18 to 45, will be selected using convenient sampling. Informed consent will be obtained from all participants. Participants will be divided into two …
Digital Navigators for Acceptance and Competence Development with Mental Health Apps
The goal of this clinical trial is to learn if and how so called "Digital Navigators" (DN) can help general practitioners, outpatient psychiatrists and psychologists as well as their treated patients to use digital mental health apps (DiGAs) and integrate it into their treatment. The main questions it aims to …
Perturbation-Based Treadmill Training to Prevent Unrecovered Falls in Geriatric Patients
The goal of this clinical trial is to determine the effectiveness of perturbation-based balance training (PBT) in preventing unrecovered falls among geriatric patients aged ≥70 years with a prospective fall risk of ≥40%. The study will also assess the safety and feasibility of PBT. The main research questions are: A …
Standard Treatment for Non-specific Low Back Pain Combined With Multimodal Osteopathy Treatment on Pain Intensity and Functional Capacity
Background: Low back pain is one of the most common musculoskeletal health problem with the highest prevalence in the adult population; globally, it represents a relevant cause of medical, social and economic burden. The aim of the proposed study is to determine the effect of a standard treatment for non-specific …
Emergency Stroke Unit for Acute Cerebrovascular Events ( ESU-ACE-B )
To compare the door-to-puncture time of patients with hyperacute ischemic stroke (between 4.5-6 hours after the onset of symptoms) treated in a standard stroke unit adherent to guidelines versus treated in Emergency Stroke Unit (a new stroke unit based on low-field magnetic resonance imaging).
Evaluation of Self-assembling Peptides Versus Amorphous Calcium Phosphate in the Treatment of White Spot Lesions
This clinical trial aims to compare the effectiveness of two remineralizing treatments for white spot lesions (WSLs) on the enamel surfaces of the front teeth. WSLs are early signs of tooth decay, often appearing after orthodontic treatment with braces. These white spots may persist for years and affect the esthetic …
Post Burn Cubital Tunnel Syndrome Response to High Intensity Laser Therapy Versus Shock Wave Therapy
Significant morbidity in burn patients occurs frequently because of Post burn nerve entrapment syndromes. Nerve entrapment arises due to direct compression because of edema; they may also present due to scar tissue formation. Burns of the forearm and elbow are associated with swelling, redness and pain. In second to third-degree …
HYBRID TELE-REHABILITATION VERSUS CLINIC-BASED THERAPY IN PATIENTS WITH LUMBAR RADICULOPATHY: A RANDOMIZED CONTROLLED TRIAL
A single blinded clinical randomized trial. A single blinded trained investigator examined all patients and collect all data to eliminate inter- investigator error. Patients will be divided according to the treatment procedure into two groups equal in numbers to investigate a comparative effect of hybrid tele-rehabilitation to clinicbased therapy in …
Evaluation of Maxillary Posterior Teeth Intrusion by Skeletally Anchored Mousetrap Appliance in Adult Patient With Anterior Open Bite.
Aim of the study: This clinical study aims to evaluate the dental, skeletal, and soft tissue effects of the Mousetrap appliance on the intrusion of maxillary posterior teeth in adult patients with anterior open bite. Material and methods: An uncontrolled clinical trial will be conducted involving 20 participants aged 15 …
