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Found 64,778 clinical trials
K Karen L Kesten, MS

Target ADHD Executive Working Memory Replication Study

The proposed study will replicate target engagement as assessed in the first phase while also determining if it correlates with clinically meaningful improvements in ADHD dysfunction

12 - 18 years of age All Phase N/A
C Chariklia K Deli, PhD

Postbiotics Supplementation, Gut Microbiota Composition, and Exercise-induced Inflammation

This study will investigate the effect of postbiotics supplementation on gut microbiota (GM) composition, exercise-induced oxidative stress and performance following eccentrically biased exercise. The study will be a cross-over, randomized, double-blind, controlled study that will be conducted in two cycles. Participants will be randomly assigned into one of the two …

18 - 45 years of age All Phase N/A
D David Meister, DDS

OsteoGen Plug vs. Freeze-dried Bone Allograft With Collagen Barrier

The study will be a multi-site, randomized, two-arm, controlled clinical trial using OsteoGen® Plug (Test) vs Freeze-dried Bone Allograft with collagen barrier (Control) for alveolar ridge preservation (ARP) in posterior extraction sites with intact buccal cortical plates.

18 - 75 years of age All Phase N/A

TRADE Trial - Tree Nut Immunotherapy Route Development and Evaluation

Tree nut immunotherapy Route Assessment and DEvelopment (TRADE) is a randomized controlled trial that evaluates the efficacy and safety of sublingual immunotherapy and lower, more tolerable, doses of oral immunotherapy than currently in use.

1 - 16 years of age All Phase N/A
A Amy Megerle

Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of CNP-106 in Subjects With Myasthenia Gravis

Phase 1b/2a First-in-Human (FIH) clinical trial to assess the safety, tolerability, pharmacodynamics (PD), and efficacy of multiple ascending doses of CNP-106.

18 - 75 years of age All Phase 1/2
L Lise Laclautre

Use of Virtual Reality Mask During Blood and Skin Allergic Tests in 7 to 13 Children

Main objective : Evaluate the effect of using a virtual reality mask during the blood test and pricks tests in allergic children aged from 7 to 13 years. Hypothesis : Using virtual reality mask during blood test and pricks tests for allergic kids from 7 to 13 would reduce anxiety …

7 - 13 years of age All Phase N/A
M Marisa Bittoni, PhD

Evaluating the Impact of a Virtually Supervised Exercise Intervention and Group Counseling on Inflammation and the Microbiome of Smokers at High Risk for Lung Cancer, BE FIT Trial

This phase II trial evaluates how a virtually supervised exercise intervention in combination with group counseling affects inflammation and the bacterial composition (microbiome) of the gut in smokers who are at high risk for lung cancer. Physical exercise has been shown to reduce lung cancer development and to have beneficial …

40 - 80 years of age All Phase N/A
L Laurie Medard

Controlled Study of Upper and Lower Limb Movements in Patients With Neurological Pathologies

The main aim of the study is to validate the algorithms developed to analyze the signals from the various sensors contained in the magneto-inertial control units and reconstruct upper and lower limb movements under different normal and pathological conditions.

2 years of age All Phase N/A
A Ahmed Abdelhamed Helal Mohamed, MSc

Effect of Early Administration of Albumin 20% Versus Crystalloid

Sepsis and septic shock are global health problems, leading to a high mortality rate. They are often associated with extremely low blood pressure and multiple organ dysfunctions, which are the main causes of death in critically ill patients. Fluid resuscitation is one of the most critical treatments for patients with …

18 - 60 years of age All Phase N/A
A Anuradha V. Khadilkar, MBBS,MD

Effect of Micronutrient Supplementation on Nerve Conduction Velocity in T1D- RCT

Type 1 diabetes can complicate to peripheral neuropathy due to preferential involvement of small unmyelinated nerve fibers (pain and temperature sensation) followed by myelinated nerve fibers (vibration and proprioception). The SEARCH for diabetes in youth study found diabetic neuropathy in 7% of T1D youth. The clinical form of peripheral neuropathy …

10 - 22 years of age All Phase N/A

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