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Found 64,778 clinical trials
D Dionne Williams, PhD

iHERO Study: Insurance, Health and Economic Resources Online for Emerging Adults With Type 1 Diabetes

This research study aims to test a financial and health insurance iHERO Toolkit for young adults with type1 diabetes. The iHERO Toolkit was developed over one year with the type 1 diabetes community, The Diabetes Link organization, and experts. Now, the investigators want to understand the impact of the iHERO …

18 - 30 years of age All Phase N/A
M Mostafa Borahay, MD, PhD

Opioid Use After Laparoscopic Salpingectomy

The purpose of this study is to evaluate patient-reported post-operative pain scores following minimally invasive tubal sterilization procedures to determine if a multimodal, non-opioid pain control regimen is non-inferior to a pain control regimen including opioids. The study team hypothesizes that with extensive counseling on pain management, multimodal medication use, …

18 years of age Female Phase 4
A Anthony Wade

Cognitive Behavioral and Faith Fellowship to Improve Thy Health

Investigators will examine the efficacy of a faith-based depression intervention, in reducing symptoms of depression among African American adults in Wisconsin. Twelve church groups, each with 10 people (N=120) will be invited to participate. This intervention will be the first evidence-based, faith-based intervention designed for African Americans if validated.

18 years of age All Phase N/A
J Jiang Longwei, Master

A Study of Tumor Neoantigen-specific T Cells in the Treatment of Advanced Solid Tumors

The goal of this clinical trial is to learn if tumor neoantigen-specific T cells can treat patients with advanced solid tumors. The main questions it aims to answer are: Evaluate the safety of intravenous infusion of tumor neoantigen-specific T cells in the treatment of advanced solid tumors such as ovarian …

18 - 75 years of age All Phase N/A
A Arshad Nawaz Malik, PhD

Effects of Brain Training Games on Cognitive Function and Quality of Life in MCI

The study aims to determine the effects of brain training games on cognitive function and Quality of life among older adults with MCI.

50 - 80 years of age All Phase N/A
F Francesca del Bufalo, MD

Allogeneic Second-generation CD19-CAR T Cells for Pediatric Relapsed/Refractory B-ALL

This is a phase I, open label study to evaluate the safety, identify the recommended dose (RD) and obtain preliminar evidence of the efficacy of allogeneic, CD19-directed Chimeric Antigen Receptor T (alloCAR-T) cells in pediatric and young adults patients with relapsed/refractory B-cell precursor Acute Lymphoblastic Leukemia (BCP-ALL).

1 - 35 years of age All Phase 1
G Geraldine Horigan, PhD

Bioavailability and Bioactivity of Orange Polyphenols

This study will provide a greater insight into the relationship between orange consumption and health (particularly gut health) and could be used to help with the development of novel food products. Oranges are a rich source of (poly)phenols, and although the advantages of a (poly)phenol-rich diet are well-established, the bioavailability …

18 - 75 years of age All Phase N/A
A Anwar Khan

Efficacy of Eye Movement Desensitization & Reprocessing vs Cognitive Behavioral Therapy in Post-Traumatic Stress and Comorbid Disorders in Pakistan

This Randomized Controlled Trial will check the efficacy of Eye Movement Desensitization & Reprocessing vs Cognitive Behavioral Therapy in Post-Traumatic Stress and Comorbid Disorders in Pakistan

18 - 60 years of age All Phase N/A

Comparative Study Between Intravenous Granisetron and Ondansetron on Their Effect on Hemodynamics and Shivering After Spinal Anesthesia in Elective Cesarean Delivery

Spinal anesthesia is commonly used in cesarean section surgeries . The most important adverse effects of spinal anesthesia are hypotension and bradycardia caused by sympathetic blockade, with an incidence of about 55-100% . However, blocking the venous return by the gravid uterus increases the risk of hypotension. Spinal anesthesia-induced hypotension …

years of age Female Phase N/A
A Ante Lisicic, MD

Comparison of Expandable and Fixed Size Cryoballoon for the Treatment of Paroxysmal Atrial Fibrillation

The goal of this clinical trial is to compare two different, market approved, cryoballoon devices for the treatment of paroxysmal atrial fibrillation (AF). The main aims of the study are: to compare the efficacy of two ablation devices (acute and 1 year success rates) to compare the procedural characteristics (procedure …

18 - 80 years of age All Phase N/A

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