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Found 64,778 clinical trials
C Chien-Chung Yang

Investigating the Impact of Acupuncture on the Quality of Life of Primitive Headaches Patients

Primary headache is one of the most common neurological diseases in modern society, which seriously affects the patient's quality of life. Although the use of painkillers can alleviate primary headache symptoms, it may also cause drug dependence. Therefore, alternative therapies that do not rely on drugs have attracted increasing attention …

18 years of age All Phase N/A
M Melchor Carbonell, Ph.D.

Study to Estimate Seedchrony's Predictive Capacity in the Success of Embryo Implantation.

In Vitro Fertilization (IVF) success is below 40%, with Embryo Transfer the leading cause of IVF failure. This clinical investigation aims to evaluate if the levels of an intrauterine biomarker dissolved in the uterine fluid (alone or as a complex biological marker) can predict the outcome of embryo transfer.

18 - 35 years of age Female Phase N/A
J Junliang Fu, MD

The Treatment of PD-1 Antibody Combined With Peg-IFNα in NAs-suppressed CHB Patients

This is a prospective, open-labled, randomized controlled study to assess efficacy and safety of treatment with Sintilimab (PD-1 antibody) combined Peg-IFNα-2b in CHB patients on stable NAs treatment.

18 - 65 years of age All Phase N/A
K Kasper Staberg Madsen, MD

Metformin Treatment of Patients With Hand Osteoarthritis

To compare metformin (2 g daily), or maximum tolerated dose, for 16 weeks with placebo as a treatment of hand osteoarthritis symptoms.

18 years of age All Phase 3
R Roland PEYRON, PhD

Neuromodulation in Patients With Neuropathic Pain and Depression.

High-frequency repetitive transcranial magnetic stimulation of the primary motor cortex has shown its effect on refractory neuropathic pain, and rTMS of the dorsolateral prefrontal cortex is commonly used for treatment-resistant depression. The treatment for patients suffering from neuropathic pain and depression, concomitantly, still needs to be studied, as there are …

18 - 85 years of age All Phase N/A
L Lisa C Krishnamurthy, PhD

Biomarkers of Reaction To HIIT Exercise

Stroke survivors with lower limb disability can improve their walking speed with high-intensity interval training (HIIT) rehabilitation therapy. However, some individuals may not respond to HIIT even when fully adherent to the program. To address this, the investigators propose to build a predictive model that identifies if a Veteran with …

18 - 80 years of age All Phase N/A
J Josefina Arroyo

Fungal Fiber for Gut Health

This study compares effects of plant based fiber vs fungi based fiber on clinical outcomes related to gut function (immunity, emotions, stress) and explores the role of gut microbiome structure and function on individual responses.

38 - 48 years of age Female Phase N/A
J Jingyan Yao

A Clinical Trial to Evaluate the Efficacy and Safety of Defocusing Lenses in Delaying Myopia Progression

The objective of this clinical trial was to evaluate the efficacy and safety of defocusing lenses for delaying myopia progression in children and adolescents. A total of 156 subjects meeting the requirements of the study protocol were included. During the study, subjects were required to wear the test product (defocus …

8 - 13 years of age All Phase N/A
S Shiren Sun

Efficacy of Immunosuppressive Therapy for IgA Nephropathy With Stage 3 or 4 CKD

The purpose of this clinical trial is to evaluate the long-term efficacy and safety of low-dose oral corticosteroids combined with cyclophosphamide therapy and low-dose corticosteroids monotherapy, on a background of maximal RAS inhibitor therapy, for IgA nephropathy with stage 3 or 4 chronic kidney disease.

18 years of age All Phase 3
D Demian Kogutek, PhD

A Study of the Efficacy of IAMT as an Assessment Tool for Prediction of Progression of Parkinson's Disease

The primary objective of this proposal is to examine the efficacy of Improvised Active Music Therapy (IAMT) sessions as an early novel tool for cognitive and motor assessment for individuals with Parkinson's Disease (PD) in neurological rehabilitation. This will be achieved by identifying subtle variations in how participants play music …

50 years of age All Phase N/A

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