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Found 65,447 clinical trials
M Madhuri Agrawal, MS

Group Advanced Care Planning Pilot for Veterans

The proposed research aims to engage participants in group educational sessions to facilitate learning of topics related to advanced care planning and to determine whether this approach is more effective than usual care alone.

18 years of age All Phase N/A
S Sue Brown, MD

AIDANET At Home Study

A randomized cross-over trial assessing glycemic control on Automated insulin delivery as Adaptive Network (AIDANET) algorithm when used in three modes: AIDANET-Fully Closed Loop (FCL), AIDANET-Hybrid Closed Loop (HCL) and AIDANET allowing a mix between FCL and HCL. There will be an Automated Insulin Delivery (AID) phase with participants using …

18 years of age All Phase N/A

Community Health Worker-led Hypertension Management

This study is to determine if hypertension management by community health workers (CHW) supported by a mobile health application and remote physician supervision is non-inferior to management by a physician for the primary outcome of improvement in systolic blood pressure. The target population is patients with hypertension in rural Guatemala. …

18 years of age All Phase N/A
B Bart CT van de Laar, MD

Sentinel Node and Organ-sparing Surgery in Stage I Colon Carcinoma

The aim of this study is to reduce the need for segmental colonic resection and its associated morbidity and mortality in patients with high-risk pT1 and low-risk pT2 colon cancer following endoscopic resection, by performing an endoscopic-assisted laparoscopic/robotic wedge resection of the residual tumor or scar, along with sentinel node …

18 years of age All Phase N/A
X XinYi Lin, Bs

Applying Mobile Healthcare Education to Improve Cutaneous Self-care Capability

The goal of this clinical interventional study is to compare the efficacy of mobile healthcare education in two ways (game-based or text-based) to improve cutaneous self-care capability in cancer patients receiving EGFR-based target therapy. The main questions it aims to answer are: Impact of different mobile healthcare education ways on …

18 years of age All Phase N/A

ASPEN-09: A Study of Evorpacept in Combination With Anti-cancer Therapies in Advanced / Metastatic Malignancies

The purpose of this study is to evaluate evorpacept with anti-cancer therapies in advanced/metastatic malignancies. The study is comprised of the following substudies: Metastatic HER2+ breast cancer (MBC) - single-arm substudy evaluating the efficacy, safety, and tolerability of evorpacept in combination with trastuzumab and chemotherapy in participants with HER2-positive metastatic …

18 years of age All Phase 1/2

Worldwide Yearly Screening for Hypospadias

The purpose of this study is to recruit approximately 20 male participants who have a history of repaired hypospadias to test the feasibility and acceptability of the Care Planning Tool within the Worldwide Yearly Screening for Hypospadias (WYSH) Web Application.

5 - 65 years of age Male Phase N/A
D Dorothy Sears, PhD

WatchWell: Simple and Practical Strategies to Reduce the Negative Health Impact of Sedentary Screen Time

The purpose of this study is to determine the feasibility, acceptability, efficacy, and participant adherence in using home-based technologies and wearable devices and simple, practical strategies to reduce the negative impact that evening screen time may have on your health.

26 years of age All Phase N/A
J Jiaxi Yang, PhD

Asian-Mediterranean Diet and Women's Health

Given the escalating high burdens of overeight and obesity, and related commobidies in Asia, Asian women with overweight/obesity is an important group for targeted intervention in promoting health and wellbeing. A study focused on Asian women at reproductive or early post-menopausal age can inform effective strategies for promoting healthy diet …

21 - 50 years of age Female Phase N/A
R Rebecca A Dore, PhD

Literacy Instruction Through Media for Everyone

The goal of this study is to determine whether an intervention to support caregivers in engaging with their children while using educational media together can improve children's early literacy skills, compared to an aligned shared book reading intervention and to no intervention. Given that early literacy skills predict children's later …

42 - 57 years of age All Phase N/A

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