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Found 65,447 clinical trials
A Amy Leader, DrPh, MPH

Peer Navigation for the Support of Metastatic Prostate Cancer Patients Undergoing Genetic Evaluation

This clinical trial evaluates whether having a trained peer navigator helps African American men with prostate cancer that has spread to other parts of the body (metastatic) understand and navigate the genetic testing process better than not having a peer navigator. Genetic testing for men with prostate cancer is very …

18 years of age Male Phase N/A
T Tanveer Kakar, MSPT-CPPT*

Chocking First Aid Management Program for Health Care Support Workers.

To determine the effect of chocking first aid awareness program on knowledge, attitude and practice of health care support workers. Despite the importance of first aid skills, there may be gaps in the knowledge of healthcare support workers regarding choking management. A well-designed program can address these gaps, ensuring that …

20 - 40 years of age All Phase N/A
L Linzee Mabrey, MD, MSc

Anti-CD14 Treatment With IC14 in Hospitalized ARDS Patients

Hospitalized patients with ARDS will be randomized to intravenous treatment with a monoclonal antibody against CD14, called IC14, or placebo. They will be followed for 28 days. The primary outcome is the day 4 oxygenation index assessed as a continuous measure.

18 years of age All Phase 2
J Jeff Healey

Targeted Therapy With Glycogen Synthase Kinase-3 Inhibition for Arrhythmogenic Cardiomyopathy

The TaRGET study is a multi-centre, prospective, randomized, double-blind, placebo-controlled trial designed to evaluate the potential therapeutic efficacy of tideglusib, a glycogen synthase kinase-3 β inhibitor, in genotype positive arrhythmogenic cardiomyopathy.

18 years of age All Phase 2
S S. Ayse Erzurum, M.D.

Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age

In children 4 to 7 years of age, to determine if treatment with 1 hour per day 6 days per week of watching dichoptic movies/shows wearing the Luminopia headset is non-inferior to treatment with 2 hours of patching per day 7 days per week with respect to change in amblyopic …

4 - 7 years of age All Phase 3
J Jimena Quinzaños Fresnedo, MD, PhD

BCI-FES for Upper Limb Rehabilitation in Chronic Stroke

The objective of this research is to evaluate the efficacy of an experimental therapy for motor recovery of the arm after a stroke, which includes the application of a functional electrical stimulation therapy coupled to P-300 based Brain-Computer Interface system (BCI-FES). For this purpose, the investigators will compare two groups, …

18 years of age All Phase N/A
K Katherine Darling, PhD

Addressing Weight Bias Internalization to Improve Adolescent Weight Management Outcomes: Randomized Pilot Trial

Weight stigma and weight bias internalization (WBI) are common among adolescents at higher weight statuses. WBI is associated with negative physical and mental health outcomes. The current study aims to test an intervention for weight stigma and WBI combined with an evidence-based adolescent weight management program. Eligible adolescents (13-17) will …

13 - 17 years of age All Phase N/A
S Sanédy Simon, MD

The Role of Skin Sodium Accumulation in Chronic Kidney Disease

This project consists of four substudies: a cohort study (A) and a sodium intake intervention (B) and a sodium excretion intervention (C) and a water intervention study (D). The main objective of the cohort study (A) is to investigate the prognostic implications of tissue sodium accumulation in CKD patients. The …

18 years of age All Phase N/A
A Allison Zhang

Trial of Relatlimab, Nivolumab, and Ipilimumab in Patients With Asymptomatic and Symptomatic Melanoma Brain Metastases

This is a multicenter, phase II trial of relatlimab (rela), nivolumab (nivo), and ipilimumab (ipi) in patients with asymptomatic and symptomatic melanoma brain metastases.

18 years of age All Phase 2
C Claus Bistrup, MD, PhD

Effect Camostat for Kidney Protection in Chronic Kidney Disease

This clinical trial aims to evaluate the effects of Camostat Mesylate, a serine protease inhibitor, in patients with chronic kidney disease (CKD) and proteinuria. Proteinuria accelerates CKD progression and increases cardiovascular risks. By inhibiting serine protease activity and tubular complement activation, camostat may mitigate progressive kidney injury, potentially improving clinical …

18 years of age All Phase 2

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