Advanced Filters
noise
Found 64,778 clinical trials

Effectiveness of Combined Tobacco Treatment in Hospitalized Subjects

In the 20th century, tobacco caused the death of 100 million people worldwide and it is estimated that it will be responsible for 1 billion deaths in the 21st century[1]. Currently 8 million people die each year from smoking, 7 million are associated with active smoking [2], thus being the …

18 years of age All Phase 4
D Dr.Wang

ERK Inhibitor JSI-1187 in Advanced Solid Tumors

JSI-1187-101 phase 1 study

18 - 75 years of age All Phase 1
C Chima Oluigbo, MD

Focused Ultrasound Pallidotomy for Dyskinetic Cerebral Palsy in Pediatric and Young Adult Subjects

The primary objective of the proposed study is to evaluate the safety of ExAblate Transcranial MRgFUS as a tool for creating bilateral or unilateral lesions in the globus pallidus (GPi) in patients with treatment-refractory secondary dystonia due to dyskinetic cerebral palsy

8 - 22 years of age All Phase N/A
B Baijie Xu, PhD.

A Clinical Study of JS005 in Patients With Ankylosing Spondylitis

This is a multicentre, randomized, double-blind, parallel, placebo-controlled Phase II clinical study of 261 adults with active ankylosing spondylitis to evaluate the efficacy and safety of JS005 in the treatment of active ankylosing spondylitis.

18 - 75 years of age All Phase 2

6% Hydroxyethyl Starch (130/0.4) Coload for Postspinal Anesthesia Hypotension

The purpose of this study is to investigate the ED50 and ED90 for an effective 6% Hydroxyethyl starch (130/0.4) coload infusion dose for postspinal anesthesia hypotension in patients undergoing cesarean section.

18 - 40 years of age Female Phase N/A
K Katalin Kiss, MD

Comparison of Two Different External Clearance Markers - Mannitol and Iohexol for Measuring Glomerular Filtration Rate

GFR is the best parameter of the real kidney function. Measurements, however are time-consuming and have limited capacity. Patients treated in the intensive care units often have more than one organ-insufficiency and acute kidney injury (AKI) has an incidence of up to 70 %. GFR changes dynamically and this is …

18 years of age All Phase N/A
L Luxiang Wang

Evaluate the Efficacy and Safety of Allogeneic Haematopoietic Stem Cell Transplantation With FBM Conditioning for MDS

To assess the safety and efficacy of FLU-BU-MEL as a conditioning regimen for allogeneic hematopoietic stem cell transplantation in patients with untreated MDS-EB or IPSS-R that is intermediate-risk (>3.5 points), high-risk, or very high-risk. The investigators conducted this clinical trial.There will be three phases to this trial: screening, therapy, and …

18 - 65 years of age All Phase 2
S Sezer Avcı, 1

Study of the Effect of Compassion-Based Education Program Applied to Mothers of Children Diagnosed With Cerebral Palsy

Purpose of the study; The aim of this study is to examine the effect of a compassion-based education program applied to mothers of children with cerebral palsy on compassion fatigue, depression, and psychological resilience.

years of age Female Phase N/A
W Wing Sze Ho, M.Sc

rTMS Response Trajectories in Depression

Notwithstanding the cumulative evidence on the safety and efficacy of transcranial magnetic stimulation in depression care, the non-response rate to transcranial magnetic stimulation (TMS) amongst treatment-resistant depression has remained substantial despite the health care cost and time incurred. There remains a compelling clinical need to find valid biomarkers to inform …

18 - 64 years of age All Phase N/A
C Cristina Rey-Reñones, PhD

Online Formation in Cardiopulmonary Resuscitation in a Rural Area.

Background: Sudden death due to cardiorespiratory arrest has a high mortality and in most cases occurs in out-of-hospital. Cardiopulmonary resuscitation (CPR) initiated immediately by witnesses doubles survival. However, rural areas present different challenges regarding the arrival of emergency services. As a result, the rural population could benefit from basic CPR …

18 years of age All Phase N/A

Simplify language using AI