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Found 65,447 clinical trials

ONO-4538 Study in Patients With Richter's Transformation

Investigate the efficacy and safety of ONO-4538 in patients with Richter's transformation

18 years of age All Phase 2

Safety and Impact of Low Resistance Exercise Training on Quality of Life in Pulmonary Arterial Hypertension

The purpose of the study is to learn more about how low-resistance training impacts frailty and the quality of life of people with pulmonary arterial hypertension (PAH). Low-resistance training is an evidence-based approach that may help patients improve their functional ability.

18 years of age All Phase N/A

Development of MRF for Characterization of Brain Tumors After Radiotherapy

The purpose of this study is to discover the potential convenience and ease of using a Magnetic Resonance Imaging (MRI) technique, named Magnetic Resonance Fingerprinting (or MRF), to achieve high-quality images within a short scan time of 5 min for viewing the entire brain. This is an advanced quantitative assessment …

21 - 60 years of age All Phase N/A
Y Yesmine Amara (principal investigator), PhD student

Distraction With Virtual Reality From Pain and Anxiety for Patients With Hematological Malignancies

The goal of this clinical trial] is to study the effectiveness of Virtual Reality (VR) in reducing pain and anxiety during painful procedures for patients with hematological malignancies The main question[s] it aims to answer are: Does VR effectively reduce pain during painful procedures for patients with hematological malignancies ? …

6 years of age All Phase N/A
G Gwen Duytschaever

The Safety And Efficacy Of A Probiotic Intervention On Lactulose Hydrogen Breath Test-Positive Patients And Related Gastrointestinal Symptoms

The goal of this study is to test the effect of a probiotic formulation on gastrointestinal symptoms, gut and small intestine microbiota in participants suffering from small intestinal bacterial overgrowth (SIBO). Two doses of probiotic will be evaluated against placebo.

18 - 65 years of age All Phase N/A
D Dr. M.N. Kerstens

Subtyping Primary Aldosteronism With Para-chloro-2-[18F]Fluoroethyl-etomidate

The goal of this clinical trial is to investigate the uptake characteristics of [18F]CETO in adrenal tissue in patients with two different subtypes of primary aldosteronism. The main questions it aims to answer are: What are the uptake characteristics of [18F]CETO in adrenal tissue in patients with primary aldosteronism? What …

18 years of age All Phase 1/2
S Siew Chen Ling

Inspire Singapore Study

Prospective, multicenter, open-label study designed to confirm device performance of Inspire system in Singapore.

21 years of age All Phase N/A
A Asmaa Bakr elshaf3y

Therapeutic Effect of Manuka Honey Oral Rinse on Fibroblast Growth Factor-21 in Periodontitis Patients Undergoing Hemodialysis

Chronic Kidney Disease (CKD) has a strong association with chronic periodontitis, an oral disease causing tooth loss linked to inflammation and malnutrition. While periodontitis affects 12.7% of the general population, its prevalence can rise to 39% in certain racial groups, and a dose-response relationship exists with CKD. End Stage Renal …

18 years of age All Phase 3
A Anne-Lise ANTEMI-RIBREUX

Evaluation of the Effectiveness of Intensive Medical Follow-up with an Advanced Practice Nurse Compared with Medical Follow-up Alone in Non-severe Pulmonary Embolism.

In France, venous thromboembolism (VTE), which includes pulmonary embolism (PE) and deep-vein thrombosis (DVT), is the 3rd leading cause of cardiovascular disease, leading to major public health problems. Despite current monitoring and treatment, the recurrence rate and the rate of haemorrhagic complications remain high, at 18.5% and 12% respectively in …

18 years of age All Phase N/A
M Marcela C Viliod, Bachelor

Effects of High-intensity Exercise With Hypoxia and Taurine Supplementation on Metabolic and Mitochondrial Parameters

The prevalence of obesity in Brazil is one of the highest in Latin America. As an inflammatory disease, obesity needs to be treated, and one of the best interventions is exercise. This research aims to learn more about the effects of combining high-intensity training, recovery hypoxia, and taurine supplementation. To …

25 - 45 years of age Female Phase N/A

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