Found 64,778 clinical trials
Comparison of Conventional and 3D-printed Surgical Obturators for Maxillary Defects
This randomized controlled clinical trial aims to compare patient satisfaction and prosthetic complications associated with three types of immediate surgical obturators used in maxillectomy patients. A total of 24 patients with acquired maxillary defects will be randomly assigned to receive one of three obturator designs: (1) conventional obturators retained with …
Brain Mechanisms of Social Perception in Parkinson's Disease
Social cognition is a complex process that enables humans to interpret social information and behave appropriately in a social environment. Social cognition can be impaired in Parkinson's disease patients, worsening quality of life and relationships with those around them, even at an early stage. These alterations are manifested in particular …
Endoscopic Versus Open Lumbar Discectomy in Diabetic Patients
This study aims to compare the endoscopic versus open lumbar discectomy in diabetic patients.
Effectiveness of Exercise After an ICD
This study will test an exercise intervention (E-ICD) following an implantable cardioverter defibrillator.
Moderate Aerobic Exercise for Managing Menstrual Cycle Symptoms
The goal of this clinical trial is to evaluate the impact of moderate aerobic exercise on menstrual symptom management in sedentary women both using and not using hormonal contraceptives. The main questions it aims to answer are: Is there a reduction in physical and/or psychological menstrual cycle related symptom burden …
Treating Insomnia in Mild Cognitive Impairment
The goal of this study is to test a new way to improve sleep quality in persons living with mild cognitive impairment. The treatment combines a safe and gentle way to stimulate the brain, called transcranial magnetic stimulation, with a psychological treatment, called cognitive behavioral therapy for insomnia.
Single Session Intervention to Promote Hope
The purpose of this study is to develop a brief, self-guided single-session intervention (SSI) that targets the development of, or increase in, hope, and pilot test it for the primary outcomes of feasibility, acceptability/likeability, safety, and changes in hope, and the secondary outcomes of self-worth, empowerment, and emotional wellbeing among …
How a Single Workout Affects Gut Bugs in Women With Different Fitness Levels and Body Types
This study aims to elucidate the differences in the gut microbiome functional activity and metabolome in adult premenopausal women with distinctive fitness levels and BMIs (with obesity, w/o obesity). The specific aims are as follows: Aim 1: To examine the effects of acute aerobic exercise at 60-70% heart rate reserve …
Measurement-Based Peer Supervision App for Non-Specialist Providers
The goal of this project is to enhance and evaluate the efficacy of a scalable digital solution designed to help train and support the work of non-specialist providers (NSPs), such as community health workers, to deliver therapy to individuals with anxiety and/or depression. The main questions this project aims to …
Effect of Nutritional Management on Patients With Concurrent Chemoradiotherapy for Nasopharyngeal Carcinoma
Nasopharyngeal carcinoma (NPC) is a malignant tumor that develops in the nasopharyngeal mucosal epithelium. Due to the disease itself and the impact of anti-tumor therapy, malnutrition has become a common clinical complication in patients with NPC, among which NPC patients receiving concurrent chemoradiotherapy are one of the groups with the …
