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Found 62,899 clinical trials

Efficacy and Safety Study of Nipocalimab for Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

The main purpose of this study is to evaluate the safety and efficacy of nipocalimab compared to placebo in delaying relapse in adults with chronic inflammatory demyelinating polyneuropathy (CIDP) who initially respond to nipocalimab in Stage A.

18 years of age All Phase 2/3

Genomics and COVID-19 Vaccine Adverse Events

Vaccines routinely used are extremely safe; however, severe adverse events to vaccines do occur. As vaccination against COVID-19 has begun, adverse events to the vaccine, particularly Guillain-Barré syndrome (GBS), vaccine-induced immune thrombotic thrombocytopenia (VITT)/thrombosis with thrombocytopenia syndrome (TTS), and myocarditis/pericarditis, after COVID-19 vaccination have been reported worldwide. Study hypothesis: there …

5 - 99 years of age All Phase N/A
J Julieta Hoveyan, MD

Rare Embryonal Tumors of the Central Nervous System: International Registry

Central nervous system (CNS) tumors are the most common solid malignancies among children. Although some types of CNS tumors like medulloblastomas and low-grade gliomas are widespread and well-studied, there is a huge number of rare diseases that need further research. This international registry aims to establish a large multicenter database …

1 - 25 years of age All Phase N/A
X Xiafang Chen, Ph.D

Long Term Health Cohort of Premature Infants

Establish a clinical diagnosis and treatment and long-term follow-up database of preterm infants, and analyze the effects of prenatal factors (including genetic characteristics, maternal diseases, etc.), postnatal diagnosis and treatment measures and family maintenance environment after discharge on preterm infant mortality and major diseases in the near and long term.

15 - 4 years of age All Phase N/A
A Anne Pagnier, MD

An International Clinical Program for the Diagnosis and Treatment of Children With Ependymoma

The overall aim of this project is to improve the outcome of patients diagnosed with ependymoma by improving and harmonising the staging and the standard of care of this patient population and to improve the investigators understanding of the underlying biology thereby informing future treatment. The program will evaluate new …

- 22 years of age All Phase 2/3
R Rebecca Hoh, M.S.

Long-term Impact of Infection With Novel Coronavirus (COVID-19)

LIINC is a study of volunteers who were previously infected with SARS-CoV-2 (also known as novel coronavirus or COVID-19) who have recovered from acute infection. The study is designed to provide a specimen bank of samples with carefully characterized clinical data. LIINC specimens will be used to examine multiple questions …

18 - 100 years of age All Phase N/A

Human Skin and Gut Mycobiome and Bacteriome Comprehensive Registry

Bacterial and fungal microbiota will be different between individual body sites; however, particular microbiome profiles both whole-body and site-specific will be unique to volunteers with a given parameter such as medical diagnosis, diet, medications taken, geographical area; etc.

18 years of age All Phase N/A

Both Short- and Long-term Outcome Differences According to Patient Frailty

The evaluation for cancer treatment successful has been used by overall survival rate and/or postoperative complications, especially surgical area. Now postoperative QOL has been more importantly required. Therefore this study was conduced to investigate the association between postoperative outcomes and patients frailty.

18 - 90 years of age All Phase N/A
C Cesar A Arias, MD, PhD, Msc

Staphylococcus Aureus Network Adaptive Platform Trial

The Staphylococcus aureus Network Adaptive Platform (SNAP) trial is an International Multi-Centered Randomised Adaptive Platform Clinical Trial to evaluate a range of interventions to reduce mortality for patients with Staphylococcus Aureus bacteraemia (SAB).

years of age All Phase 4
P Patrick IP, MBBS, MPH

KeySteps@JC Phase One Follow-up Study

This proposed study is a 5-year follow-up study of "KeySteps Phase One Study", which focused on bridging the gap between students from privileged and underprivileged families. This study will investigate the long-term effects of early childhood interventions provided during the kindergarten stage on primary school children and their families and …

6 - 13 years of age All Phase N/A

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