Advanced Filters
noise
Found 65,259 clinical trials
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Perception, Sensation, Cognition and Action in Humans

Background When people see and hear, the brain changes signals from the eyes and ears into perceptions and thoughts. No one fully understands how this happens. Researchers want to explore how healthy brains process sights and sounds. Objectives To explore how people understand what they see and hear when the …

13 - 65 years of age All Phase N/A
z zhi W Shen, Master

Relationship About Pregnancy Health and Offspring Developmental &Behavioral Outcomes

This topic puts forward a hypothesis: genetic and environmental factors such as major depressive disorder during pregnancy, nutritional status of vitamin A, D, E, and folic acid, intestinal microecology, and bisphenol A exposure, may affect the cognitive development level of the offspring through the genetic correlation with attention deficit hyperactivity …

3 - 72 years of age All Phase N/A

An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia

Sodium zirconium cyclosilicate has been shown to be effective and safe in adults for the treatment of hyperkalaemia, and therefore it is expected to be beneficial in children. This study will evaluate the efficacy, safety and tolerability of sodium zirconium cyclosilicate for the treatment of hyperkalaemia in children \<18 years …

- 18 years of age All Phase 3
S Stéphane Béchet, MsC

Bacteriological Evaluation of Children With Otorrhea

After pneumococcal conjugate vaccine implementation, the number of acute otitis media (AOM) episodes has decreased, but AOM still remains among the most common diagnoses in childhood. From 2% to 17% of cases of AOM feature spontaneous perforation of the tympanic membrane (SPTM). The aim of this study was to describe …

3 - 15 years of age All Phase N/A
A Alison Barnwell

Alpelisib in Pediatric and Adult Patients With Lymphatic Malformations Associated With a PIK3CA Mutation.

The main purpose of this study in participants with PIK3CA-mutated LyM is to assess the change in radiological response and symptom severity upon treatment with alpelisib film-coated tablets (FCT) as compared to placebo.

- 100 years of age All Phase 2/3
R Raj Srirajaskanthan

Mobile Application to Collect PRO Data in NET Patients

Observational trial to assess the feasibility of monitoring patient reporting symptoms via mobile devices

18 years of age All Phase N/A
S Sanjoy Chatterjee, FRCR

One Week Versus Three Week in Adjuvant Radiotherapy in Breast Cancer

Background:Moderate three week hypofractionated adjuvant radiotherapy schedule is a standard care in breast cancers. A five day schedule has been demonstrated to be iso-toxic as a standard three week schedule. Recently studies have also demonstrated the safety and feasibility of simultaneous integrated boost in this setting. This randomized trial will …

18 years of age Female Phase N/A

A Study to Evaluate the Efficacy and Safety of AD-218

The purpose of this study is to evaluate the efficacy and safety of AD-218

19 years of age All Phase 3

Ventilator-associated Tracheobronchitis Initiative to Conduct Antibiotic Evaluation

The Ventilator Associated tracheobronchitis Initiative to Conduct Antibiotic evaluation (VATICAN) trial is a national, multicenter, non-inferiority trial in ICU patients comparing antibiotic treatment for 7 days versus clinical observation without antibiotic treatment for patients with ventilator-associated tracheobronchitis.

18 years of age All Phase N/A
A Ashley Dwarka

Comparative Effectiveness of Mobile Health Smoking Cessation Approaches Among Underserved Patients in Primary Care

This study will evaluate the comparative effectiveness of three smoking cessation therapies: mobile health (mHealth) application iCanQuit, mHealth application iCanQuit + Motiv8, and the Florida quit line.

21 years of age All Phase N/A

Simplify language using AI